Indian Journal of Radiology and Imaging, Table of Contents CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2016; 26(03): 337-341DOI: 10.4103/0971-3026.190424 Neuroimaging Primary diffuse leptomeningeal oligodendrogliomatosis: A case report and literature review Authors Author Affiliations Amarnath Chellathurai Department of Radiodiagnosis, Government Stanley Medical College, Chennai, Tamil Nadu, India Jay S Vaidya Department of Radiodiagnosis, Government Stanley Medical College, Chennai, Tamil Nadu, India Gopinathan Kathirvelu Department of Radiodiagnosis, Kilpauk Medical College, Chennai, Tamil Nadu, India Periakaruppan Alagappan Department of Radiodiagnosis, Tamil Nadu Multispeciality Hospital, Omandurar, Chennai, Tamil Nadu, India Recommend Article Abstract PDF Download(opens in new window) Abstract Primary leptomeningeal oligodendrogliomatosis (PLO) is a rare low-grade intracranial and spinal canal subarachnoid neoplasm without an obvious primary neoplasm in the brain or spinal cord parenchyma. We present here the serial progression of radiological findings of this rare disease in a 2-year-old male child whose clinical status deteriorated over a period of 4 months with the main complaint of partial seizures. During this period, the MR findings progressed from mild hydrocephalus with minimal leptomeningeal enhancement to leptomeningeal multiple cystic lesions in the entire neuraxis including the spine. Keywords KeywordsLeptomeningeal gliomatosis - low-grade glioma - primary leptomeningeal oligodendrogliomatosis PDF (1604 kb) References References 1 Moore M. Diffuse cerebrospinal gliomatosis, masked by neurosyphilis. J Neuropathol Exp Neurol 1954;13:129-43. 2 Yomo S, Tada T, Hirayama S, Tachibana N, Otani M, Tanaka Y, et al. A case report and review of the literature. J Neurooncol 2007;81:209-16. 3 Riva M, Bacigaluppi S, Galli C, Citterio A, Collice M. Primary leptomeningeal gliomatosis: Case report and review of the literature. 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