Download PDF
CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2013; 34(01): 38-41
DOI: 10.4103/0971-5851.113423
CASE REPORT

Primary pulmonary rhabdomyosarcoma in children: Report of three cases with review of literature

Kadabur Nagendrappa Lokesh
Department of Medical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
,
Chennagiri S. Premalata
Department of Pathology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
,
B.S. Aruna Kumari
Department of Pediatric Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
,
L Appaji
Department of Pediatric Oncology, Kidwai Memorial Institute of Oncology, Bangalore, Karnataka, India
› Author Affiliations
› Further Information
Also available at
  PDF Download Permissions and Reprints

Abstract

Primary pulmonary rhabdomyosarcoma in children is rare. Three children aged three, nine and three years were evaluated for abnormal shadows on radiological examination with pneumothorax in two cases. Resection and histopathological examination revealed embryonal rhabdomyosarcoma in all and cystic malformation in first case. All the three children were treated with surgery and first two received adjuvant chemotherapy. The disease free duration was 160 months, 19 months and seven months respectively. The literature on primary pulmonary rhabdomyosarcoma in children was reviewed.

Keywords

Embryonal - pneumothorax - pulmonary - rhabdomyosarcoma


Publication History

Article published online:
20 July 2021

© 2013. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Hancock BJ, Di Lorenzo M, Youssef S, Yazbeck S, Marcotte JE, Collin PP. Childhood primary pulmonary neoplasms. J Pediatr Surg 1993;28:1133-6.
  • 2 Ueda K, Gruppo R, Unger F, Martin L, Bove K. Rhabdomyosarcoma of lung arising in congenital cystic adenomatoid malformation. Cancer 1977;40:383-8.
  • 3 Hartman GE, Shochat SJ. Primary pulmonary neoplasms of childhood: A review. Ann Thorac Surg 1983;36:108-19.
  • 4 Maurer HM, Moon T, Donaldson M, Fernandez C, Gehan EA, Hammond D, et al. The intergroup rhabdomyosarcoma study: A preliminary report. Cancer 1977;40:2015-26.
  • 5 Andrassy RJ, Wiener ES, Raney RB, Lawrence W, Lobe TE, Corpron CA, et al. Thoracic sarcomas in children. Ann Surg 1998;227:170-3.
  • 6 McDonald S Jr, Heather JC. Neoplastic invasion of the pulmonary veins and left auricle. J Pathol Bacteriol 1939;48:533-43.
  • 7 Fallon G, Schiller M, Kilman JW. Primary rhabdomyosarcoma of the bronchus. Ann Thorac Surg 1971;12:650-4.
  • 8 Thomas WJ, Koenig HM, Ellwanger FR, Lightsey AL. Primary pulmonary rhabdomyosarcoma in childhood. Am J Dis Child 1981;135:469-71.
  • 9 Crist WM, Raney RB Jr, Newton W, Lawrence W Jr, Tefft M, Foulkes MA. Intrathoracic soft tissue sarcomas in children. Cancer 1982;50:598-604.
  • 10 Williams RA. Embryonal rhabdomyosarcoma occurring in cystic adenomatoid malformation. Pediatr Pathol 1986;5:118-9.
  • 11 Allan BT, Day DL, Dehner LP. Primary pulmonary rhabdomyosarcoma of the lung in children. Report of two cases presenting with spontaneous pneumothorax. Cancer 1987;59:1005-11.
  • 12 Shariff S, Thomas JA, Shetty N, D′Cunha S. Primary pulmonary rhabdomyosarcoma in a child, with a review of literature. J Surg Oncol 1988;38:261-4.
  • 13 Hedlund GL, Bisset GS 3 rd , Bove KE. Malignant neoplasms arising in cystic hamartomas of the lung in childhood. Radiology 1989;173:77-9.
  • 14 Murphy JJ, Blair GK, Fraser GC, Ashmore PG, LeBlanc JG, Sett SS, et al. Rhabdomyosarcoma arising within congenital pulmonary cysts: Report of three cases. J Pediatr Surg 1992;27:1364-7.
  • 15 McDermott VG, Mackenzie S, Hendry GM. Case report: Primary intrathoracic rhabdomyosarcoma: A rare childhood malignancy. Br J Radiol 1993;66:937-41.
  • 16 Bogers AJ, Hazebroek FW, Molenaar J, Bos E. Surgical treatment of congenital bronchopulmonary disease in children. Eur J Cardiothorac Surg 1993;7:117-20.
  • 17 Doval DC, Kannan V, Acharya R, Mukherjee G, Chandrashekhar M, Bapsy PP. Bronchial embryonal rhabdomyosarcoma: A case report. Acta Oncol 1994;33: 832-33.
  • 18 Noda T, Todani T, Watanabe Y, Uemura S, Urushihara N, Morotomi Y, et al. Alveolar rhabdomyosarcoma of the lung in a child. J Pediatr Surg 1995;30:1607-8.
  • 19 d′Agostino S, Bonoldi E, Dante S, Meli S, Cappellari F, Musi L. Embryonal rhabdomyosarcoma of the lung arising in cystic adenomatoid malformation: Case report and review of the literature. J Pediatr Surg 1997;32:1381-3.
  • 20 Ozcan C, Celik A, Ural Z, Veral A, Kandiloðlu G, Balik E. Primary pulmonary rhabdomyosarcoma arising within cystic adenomatoid malformation: A case report and review of the literature. J Pediatr Surg 2001;36:1062-5.
  • 21 Iqbal Y, Abdullah MF, Al-Jadaan S, Trabichi H, Al Omari A, Al-Sudairy R. Embryonal rhabdomyosarcoma of the lung in a child: Case report and literature review. Ann Saudi Med 2002;22:91-3.
  • 22 Doladzas T, Arvelakis A, Karavokyros IG, Gougoudi E, Pikoulis E, Patsouris E, et al. Primary rhabdomyosarcoma of the lung arising over cystic pulmonary adenomatoid malformation. Pediatr Hematol Oncol 2005;22:525-9.
  • 23 Revillon Y, Jan D, Plattner V, Sonigo P, Dommergues M, Mandelbrot L, et al. Congenital cystic adenomatoid malformation of the lung: Prenatal management and prognosis. J Pediatr Surg 1993;28:1009-11.
  • 24 Aterman K, Patel S. Striated muscle in the lung. Am J Anat 1970;128:341-58.
  • 25 Krous HF, Sexauer CL. Embryonal rhabdomyosarcoma arising within a congenital bronchogenic cyst in a child. J Pediatr Surg 1981;16:506-8.