Subscribe to RSS

DOI: 10.4103/0971-5851.73601
Thyroiditis mimicking relapse of acute lymphoblastic leukemia: Gallium-67 scan suggested the diagnosis
Source of Support Nil.
Abstract
Acute lymphoblastic leukemia (ALL) is the most common form of leukemia in childhood and accounts for 85% of cases. ALL frequently presents as an infectious process with an abrupt onset of high fever. Thyroid disease has been reported to have a strong association with acute leukemia. Gallium (Ga-67) citrate has been used in the investigation of patients labeled as having pyrexia of unknown origin. We report a case of a 13-year-old female patient who presented with fever and suspected disease relapse after a period of disease remission; however, gallium-67 citrate whole body scan suggested the diagnosis of thyroiditis.
Publication History
Article published online:
19 November 2021
© 2010. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Bernard EJ, Nicholls WD, Howman-Giles RB, Kellie SJ, Uren RF. Patterns of abnormality on bone scans in acute childhood leukemia. J Nucl Med 1998;39:1983-6.
- 2 Berkow R. The acute leukaemias. The Merck Manual. 14th ed. Rahway, N.J.: Merck and Co. Inc.; 1982. p. 1139-42.
- 3 Willems E, Valdes-Socin H, Betea D, Beckers A, Beguin Y. Association of acute leukemia and autoimmune polyendocrine syndrome in two kindreds. Leukemia 2003;17:1912-4.
- 4 Byrd JC, Dow NS, Gaertner E, Hargis JB, Raber TR, Burrell L, et al. Leukemic thyroiditis as the initial relapsing sign in a patient with acute lymphocytic leukemia and blast expression of the neural cell adhesion molecule. Am J Hematol 1997;55:212-5.
- 5 Moskowitz C, Dutcher JP, Wiernik PH. Association of thyroid disease with acute leukemia. Am J Hematol 1992;39:102-7.
- 6 Matthies A, Nikpoor N. Isotope imaging in inflammatory thyroid disorders.: Joint Program in Nuclear Medicine; 1997.
- 7 Castellucci RP, Gardner DF, Haden HT, Adler RA. Autoimmune thyroiditis manifested as a systemic febrile illness: Diagnosis by gallium scan and fine needle aspiration biopsy. South Med J 1989;82:647-9.
- 8 Achong DM, Snow KJ. Gallium-avid painless thyroiditis in a patient with AIDS. Clin Nucl Med 1994;19:413-5.