Staphylococcal Small Colony Variants from a Libyan Hospital

Mohamed O Ahmed; Ezzeddin Sh Aghila; Asma K Elramalli; Mohamed S Agdih

doi:10.4103/0974-2727.154804

Journal of Laboratory Physicians, Table of Contents

CC BY-NC-ND 4.0 · J Lab Physicians 2015; 7(01): 068-069
DOI: 10.4103/0974-2727.154804

Letters to Editor

Staphylococcal Small Colony Variants from a Libyan Hospital

Mohamed O Ahmed

Departments of Microbiology and Parasitology, Faculty of Veterinary Medicine, University of Tripoli, Tripoli, Libya

,

Ezzeddin Sh Aghila

Laboratory Division, Burns and Plastic Surgery Centre, Tripoli, Libya

,

Asma K Elramalli

Tripoli Medical Centre, Tripoli, Libya

,

Mohamed S Agdih

Laboratory Division, Burns and Plastic Surgery Centre, Tripoli, Libya

› Author Affiliations

Abstract

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References

REFERENCES
1 Proctor RA, von Eiff C, Kahl BC, Becker K, McNamara P, Herrmann M, et al. Small colony variants: A pathogenic form of bacteria that facilitates persistent and recurrent infections. Nat Rev Microbiol 2006;4:295-305.
2 Kahl BC. Small colony variants (SCVs) of Staphylococcus aureus - A bacterial survival strategy. Infect Genet Evol 2014;21:515-22.
3 Garcia LG, Lemaire S, Kahl BC, Becker K, Proctor RA, Denis O, et al. Antibiotic activity against small-colony variants of Staphylococcus aureus: Review of in vitro, animal and clinical data. J Antimicrob Chemother 2013;68:1455-64.
4 Seifert H, von Eiff C, Fätkenheuer G. Fatal case due to methicillin-resistant Staphylococcus aureus small colony variants in an AIDS patient. Emerg Infect Dis 1999;5:450-3.
5 Yagci S, Hascelik G, Dogru D, Ozcelik U, Sener B. Prevalence and genetic diversity of Staphylococcus aureus small-colony variants in cystic fibrosis patients. Clin Microbiol Infect 2013;19:77-84.
6 Onyango LA, Hugh Dunstan R, Roberts TK, Macdonald MM, Gottfries J. Phenotypic variants of staphylococci and their underlying population distributions following exposure to stress. PLoS One 2013;8:e77614.
7 von Eiff C. Staphylococcus aureus small colony variants: A challenge to microbiologists and clinicians. Int J Antimicrob Agents 2008;31:507-10.
8 Tuchscherr L, Heitmann V, Hussain M, Viemann D, Roth J, von Eiff C, et al. Staphylococcus aureus small-colony variants are adapted phenotypes for intracellular persistence. J Infect Dis 2010;202:1031-40.
9 Sendi P, Proctor RA. Staphylococcus aureus as an intracellular pathogen: The role of small colony variants. Trends Microbiol 2009;17:54-8.