ABSTRACT
Background: Dyslipidemia has been established as a well-known traditional risk factor for cardiovascular
disease in chronic kidney disease patients.
Aim: This study investigated the impact of Hatha yoga exercise on lipid parameters in
patients with end-stage renal disease (ESRD) on hemodialysis.
Materials and Methods: This prospective randomized study consisted of 33 ESRD patients in the Hatha yoga exercise group that was matched with 35 ESRD patients in the control group. Serum
total cholesterol, triglycerides, low-density lipoprotein (LDL)-cholesterol, and high-density
lipoprotein (HDL)-cholesterol were determined at baseline (0 month) and after 4 months.
Results: Comparing values after 4 months versus baseline in the prehemodialysis Hatha yoga
exercise group, there was found a significant decrease in total cholesterol from 5.126
± 0.092 mmol/l to 4.891 ± 0.072 mmol/l (-4.58%; P = 0.0001), triglycerides from 2.699 ± 0.078 mmol/l to 2.530 ± 0.063 mmol/l (-6.26%;
P = 0.0001), LDL-cholesterol from 2.729 ± 0.083 mmol/l to 2.420 ± 0.066 mmol/l (-11.32%;
P = 0.0001), and total cholesterol/HDL-cholesterol ratio from 5.593 ± 0.119 mmol/l
to 4.907 ± 0.116 mmol/l (-12.26%; P = 0.047). For patients in the Hatha yoga exercise group, 51.5% had normal total cholesterol
at 0 month while 70.0% had normal total cholesterol (P <0.05)after 4 four months and 54.5% of patients had normal LDL-cholesterol at 0 month
while 84.9% had normal LDL-cholesterol after 4 months (P <0.05).
Conclusion: These findings suggest that Hatha yoga exercise has preventive and beneficial effects and may be a safe therapeutic modality
in ESRD patients.
Keywords
Cardiovascular - end-stage renal disease, - hatha yoga exercise - total cholesterol