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CC BY-NC-ND 4.0 · Journal of Digestive Endoscopy 2013; 04(03): 078-081
DOI: 10.4103/0976-5042.129974
Case Report
Society of Gastrointestinal Endoscopy of India

Large gastric ulcer: Result of foreign body-induced giant cell reaction

Mona Dhakal
Department of Medicine, Sikikim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
,
Om Prakash Dhakal
Department of Medicine, Sikikim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
,
Mingma Sherpa
1   Department of Pathology, Sikikim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
,
Amlan Gupta
1   Department of Pathology, Sikikim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
,
Dhurba Bhandari
2   Department of Microbiology, Sikikim Manipal Institute of Medical Sciences, Gangtok, Sikkim, India
› Author Affiliations
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Publication History

Publication Date:
26 September 2019 (online)

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Abstract

A granuloma is an organized and compact mass of mature mononuclear phagocytes. Granulomas are reported to form in various organs and sites of the body. Granulomas in stomach are rarely encountered. Foreign body granulomas are formed as a result of reaction of the tissues to a foreign body which is immunologically inert. Food granuloma is type of foreign body granuloma which is formed in response to food particles like vegetable matters or cereals. These granulomas can be distinguished from other types of granulomas with ease because of their characteristic morphologic features. We report the case of a 29-year-old male who developed a large gastric ulcer as a result of foreign body–induced giant cell reaction, which was probably of vegetative origin. He was treated with the regimen for Helicobacter pylori, rabeprazole and sucralfate. This treatment resulted in partial healing of the ulcer with persistence of food granuloma; hence, the patient was referred for surgery.

Key words

Food granuloma - foreign body - gastric ulcer
 

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