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CC BY-NC-ND 4.0 · World J Nucl Med 2015; 14(03): 197-201
DOI: 10.4103/1450-1147.163253
Original article

The Relationship Between Some Complete Blood Count Parameters and Myocardial Perfusion: A Scintigraphic Approach

Semra Ozdemir
Department of Nuclear Medicine, Canakkale Onsekiz Mart University, Çanakkale, Turkey
,
Ahmet Barutcu
1   Department of Cardiology, Canakkale Onsekiz Mart University, Çanakkale, Turkey
,
Emine Gazi
1   Department of Cardiology, Canakkale Onsekiz Mart University, Çanakkale, Turkey
,
Yusuf Tan
Department of Nuclear Medicine, Canakkale Onsekiz Mart University, Çanakkale, Turkey
,
Hakan Turkon
2   Department of Biochemistry, Canakkale Onsekiz Mart University, Çanakkale, Turkey
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Recent studies have shown that there is a relationship between some inflammatory and biochemical markers derived from complete blood count (CBC) such as neutrophil/lymphocyte (N/L) ratio, platelet/lymphocyte (P/L) ratio, platelet distribution width (PDW), red blood cell distribution width (RDW), and coronary artery disease (CAD). The aim of this study was to determine N/L ratio, P/L ratio, PDW values, and RDW values, which are associated with myocardial perfusion in patients diagnosed with CAD. This study included 262 patients (149 with myocardial ischemia/infarction and 113 with normal myocardial perfusion) undergoing myocardial perfusion scintigraphy (MPS) with CBC within 90 days of MPS. Myocardial perfusion parameters such as summed stress score and summed difference score (SDS) were compared with N/L ratio, P/L ratio, PDW values, and RDW values. Neutrophil counts and N/L ratios were significantly higher in patients diagnosed with myocardial ischemia and/or infarct. However, there was no statistically significant relationship between myocardial perfusion abnormalities and P/L ratio, PDW values, and RDW values. This study showed that N/L ratio is related to myocardial ischemia/infarction and correlated to left ventricular ejection fraction (LVEF).

Keywords

Ejection fraction - myocardial perfusion scintigraphy - nutrophil/lymphocyte ratio


Publication History

Article published online:
21 May 2022

© 2015. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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