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CC BY-NC-ND 4.0 · World J Nucl Med 2016; 15(01): 3-6
DOI: 10.4103/1450-1147.172139
Review article

Comparison of [15O] H2O positron emission tomography and functional magnetic resonance imaging in activation studies

Authors

  • Masashi Kameyama

    1   Division of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo, Japan
    2   Division of Nuclear Medicine, Keio University, Tokyo, Japan

  • Koji Murakami

    2   Division of Nuclear Medicine, Keio University, Tokyo, Japan

  • Masahiro Jinzaki

    3   Department of Radiology, School of Medicine, Keio University, Tokyo, Japan
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[15O] H2O positron emission tomography (PET) has long been out of use in activation studies on the brain. Indeed, it is true that blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has better spatial resolution and temporal resolution than PET, as well as no radiation exposure. However, PET and fMRI differ in their scope. Compared to fMRI, [15O] H2O PET offers advantages such as being quantifiable, less deteriorated by movement, and allowing for longitudinal studies. This article aimed to reassess the merits of PET in this context.

Keywords

Arterial spin labeling - blood oxygen level dependent - cerebral blood flow - magnetic resonance imaging - positron emission tomography


Publication History

Article published online:
19 May 2022

© 2016. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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