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CC BY-NC-ND 4.0 · World J Nucl Med 2018; 17(01): 3-5
DOI: 10.4103/1450-1147.222289
Original article

Treatment response evaluation using Yttrium-90 in patients with rheumatoid arthritis of knee joint

Jong Kim
Department of Nuclear Medicine, Kim II Sung University, Pyongyang
,
Wi Kim
Department of Nuclear Medicine, Kim II Sung University, Pyongyang
,
Yong Pak
Department of Nuclear Medicine, Kim II Sung University, Pyongyang
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For radiosynovectomy, we have measured the retention time of yttrium-90 (90Y) hydroxyapatite (particle size 1–10 μm) within the knee joint space and evaluated the treatment responses in knees with rheumatoid arthritis. Radioactive measurements in the region of knee after injection of 90Y hydroxyapatite into the joint space were made with a single prove system designed to monitor radioactivity and showed retention of 90Y in the knee ranged 76.6% ±5.4% after 4 days of injection. The clinical improvements in rheumatoid arthritis of knee joint with steinbroker Stages I and II were increased as time goes by, the improvement ratio is in 72% at 6th months and 76% at 12th months after injection of 90Y 185 MBq (5 mCi) per joint.

Keywords

Knee joint - radiosynovectomy - yttrium-90 hydroxyapatite


Publication History

Article published online:
17 May 2022

© 2018. Sociedade Brasileira de Neurocirurgia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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