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CC BY-NC-ND 4.0 · South Asian J Cancer 2015; 04(01): 035-037
DOI: 10.4103/2278-330X.149949
HISTOPATHOLOGY IN ONCOLOGY : Original Article

Role of FNAC in Hepatic lesions: Risk of track metastases

Challa Vasu Reddy
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
,
Y. G. Basavana Goud
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
,
R. Poornima
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
,
Vijayalakshmi Deshmane
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
,
B. A. Madhusudhana
Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
,
M Gayathridevi
Department of Pathology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka
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Abstract

Background: Liver is one of the most common site of metastases in patients with malignancy and the evaluation of space occupying lesions (SOL) of liver in patients with malignancy is important. Its important to differentiate benign from malignant to take necessary decisions. Materials and Methods: We have performed a retrospective analysis of liver SOLs for which fine needle aspiration cytology (FNAC) was done in the year 2011. Risks and benefits associated with FNAC were evaluated. Results: We analyzed 755 patients who underwent FNAC of which 524 patients had secondary metastases to liver, 148 patients had primary hepatocellular carcinoma, 14 cases were benign neoplasms and 53 were nonneoplastic conditions. Histological correlation with FNAC was available in 112 patients. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were 93%, 90.9%, 98.9%, 58.8%, and 92.8%, respectively. Though there were no incidence of bleeding, two patients developed track metastases following FNAC. One was a case of Hepatocellular carcinoma and the other a case of metastatic breast cancer. Conclusion: FNAC was very much useful in our setup where most of the patients could not afford for Computer tomography (CT) scan and was useful in counseling them especially in patients with advanced malignancy where no active cancer directed therapy is required.

Key words

Fine Needle Aspiration Cytology liver lesions - hepatocellular carcinoma - liver metastases - track metastases


Publikationsverlauf

Artikel online veröffentlicht:
31. Dezember 2020

© 2015. MedIntel Services Pvt Ltd. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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  • References

  • 1 Bingel A. Ueber die parenchympunktion der leber. Verh Dtsch Ges Inn Med 1923;35:210-2.
  • 2 Metcalfe MS, Bridgewater FH, Mullin EJ, Maddern GJ. Useless and dangerous--fine needle aspiration of hepatic colorectal metastases. BMJ 2004;328:507-8.
  • 3 Smith EH. Complications of percutaneous abdominal fine-needle biopsy. Review. Radiology 1991;178:253-8.
  • 4 Takamori R, Wong LL, Dang C, Wong L. Needle-tract implantation from hepatocellular cancer: Is needle biopsy of the liver always necessary? Liver Transpl 2000;6:67-72.
  • 5 Llovet JM, Vilana R, Bru C, Bianchi L, Salmeron JM, Boix L, et al.; Barcelona Clínic Liver Cancer (BCLC) Group. Increased risk of tumor seeding after percutaneous radiofrequency ablation for single hepatocellular carcinoma. Hepatology 2001;33:1124-9.
  • 6 Swamy MC, Arathi C, Kodandaswamy C. Value of ultrasonography-guided fine needle aspiration cytology in the investigative sequence of hepatic lesions with an emphasis on hepatocellular carcinoma. J Cytol 2011;28:178-84.
  • 7 Mondal A. Cytodiagnosis of accuracy of hepatic malignancy by fine needle aspiration biopsy. J Ind Med Assoc 1991;89:222-4.
  • 8 Kuo FY, Chen WJ, Lu SN, Wang JH, Eng HL. Fine needle aspiration cytodiagnosis of liver tumors. Acta Cytol 2004;48:142-8.
  • 9 Gani MS, Shafee AM, Soliman IY. Ultrasound guided percutaneous fine needle aspiration biopsy/automated needle core biopsy of abdominal lesions: Effect on management and cost effectiveness. Ann Afr Med 2011;10:133-8.
  • 10 Livraghi T, Giorgio A, Marin G, Salmi A, de Sio I, Bolondi L, et al. Hepatocellular carcinoma and cirrhosis in 746 patients: Long-term results of percutaneous ethanol injection. Radiology 1995;197:101-8.
  • 11 Silva MA, Hegab B, Hyde C, Guo B, Buckels JA, Mirza DF. Needle track seeding following biopsy of liver lesions in the diagnosis of hepatocellular cancer: A systematic review and meta-analysis. Gut 2008;57:1592-6.
  • 12 Ryd W, Hagmar B, Eriksson O. Local tumour cell seeding by fine-needle aspiration biopsy. A semiquantitative study. Acta Pathol Microbiol Immunol Scand A 1983;91:17-21.
  • 13 Huang GT, Sheu JC, Yang PM, Lee HS, Wang TH, Chen DS. Ultrasound-guided cutting biopsy for the diagnosis of hepatocellular carcinoma-a study based on 420 patients. J Hepatol 1996;25:334-8.
  • 14 Ahn DW, Shim JH, Yoon JH, Kim CY, Lee HS, Kim YT, et al. Treatment and clinical outcome of needle-track seeding from hepatocellular carcinoma. Korean J Hepatol 2011;17:106-12.
  • 15 Hayashi PH, Trotter JF, Forman L, Kugelmas M, Steinberg T, Russ P, et al. Impact of pretransplant diagnosis of hepatocellular carcinoma on cadaveric liver allocation in the era of MELD. Liver Transpl 2004;10:42-8.