Download PDF
CC BY-NC-ND 4.0 · European Journal of General Dentistry 2013; 2(02): 169-173
DOI: 10.4103/2278-9626.112322
Original Article

Conservative treatment of keratocyst: A follow-up study

Vibha Singh
Department of Oral and Maxillofacial Surgery, King George′s Medical University, Lucknow, Uttar Pradesh, India
,
Shadab Mohammad
Department of Oral and Maxillofacial Surgery, King George′s Medical University, Lucknow, Uttar Pradesh, India
,
Nimisha Singh
Department of Oral and Maxillofacial Surgery, King George′s Medical University, Lucknow, Uttar Pradesh, India
,
Somdipto Das
Department of Oral and Maxillofacial Surgery, King George′s Medical University, Lucknow, Uttar Pradesh, India
› Author Affiliations
› Further Information
Also available at
  PDF Download Permissions and Reprints

Abstract

Objective: Odontogenic keratocyst (OKC) is a cyst of tooth origin with an aggressive clinical behavior, including a high recurrence rate. The OKC is well known for its tendency to recur, potential aggressive behavior and defined histopathological feature. The aim of our study is to report the outcome of conservative treatment protocol for OKC. Materials and Methods: A retrospective chart review was undertaken of all cases of OKC treated at Department of Oral and Maxillofacial Surgery, KGMU, Lucknow between 2007 and 2009. A total of 35 cases of cystic lesion were identified, which were treated by one group of surgeons. On histopathological examination 17 patients out of 35 were diagnosed as OKC. We have treated all the patients of OKC with surgical curettage followed by iodoform dressing. There was only one recurrence reported, which was further treated by resection. Clinical features and various treatment modalities of OKC are discussed. Conclusions: Enucleation followed by open packing can be used as a choice of treatment with low recurrence rate for the large keratocystic lesions. The patient should have periodic radiographic and clinical examination. In the cases of the recurrence, lesion should be treated by resection and reconstruction

Keywords

Curettage - odontogenickeratocyst - recurrence


Publication History

Article published online:
01 November 2021

© 2013. European Journal of General Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 

  • References

  • 1 Cawson RA, Odell EW. Essentials of Oral Pathology and Oral Medicine. 6 th ed., Vol. 97. New York: Churchill Livingstone; 1998.
  • 2 Daley TD, Wysocki GP, Pringle GA. Relative incidence of odontogenic tumors and oral and jaw cysts in a Canadian population. Oral Surg Oral Med Oral Pathol 1994;77:276-80.
  • 3 Kramer IR, Pindborg JJ, Shear M. The WHO Histological Typing of Odontogenic Tumours. A commentary on the Second Edition. Cancer 1992;70:2988-94.
  • 4 Tsukamoto G, Sasaki A, Akiyama T, Ishikawa T, Kishimoto K, Nishiyama A, et al. A radiologic analysis of dentigerous cysts and odontogenic keratocysts associated with a mandibular third molar. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;91:743-7.
  • 5 Zachariades N, Papanicolaou S, Triantafyllou D. Odontogenic keratocysts: Review of the literature and report of sixteen cases. J Oral Maxillofac Surg 1985;43:177-82.
  • 6 Keith DA. Macroscopic satellite cyst formation in the odontogenic keratocyst. Report of two cases. Oral Surg Oral Med Oral Pathol 1973;35:21-7.
  • 7 Oka S, Kubota Y, Yamashiro T, Ogata S, Ninomiya T, Ito S, et al. Effects of positive pressure in odontogenic keratocysts. J Dent Res 2005;84:913-8.
  • 8 Chirapathomsakul D, Sastravaha P, Jansisyanont P. A review of odontogenic keratocysts and the behavior of recurrences. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2006;101:5-9.
  • 9 Morgan TA, Burton CC, Qian F. A retrospective review of treatment of the odontogenic keratocyst. J Oral Maxillofac Surg 2005;63:635-9.
  • 10 Crowley TE, Kaugars GE, Gunsolley JC. Odontogenic keratocysts: A clinical and histologic comparison of the parakeratin and orthokeratin variants. J Oral Maxillofac Surg 1992;50:22-6.
  • 11 Brøndum N, Jensen VJ. Recurrence of keratocysts and decompression treatment. A long-term follow-up of forty-four cases. Oral Surg Oral Med Oral Pathol 1991;72:265-9.
  • 12 Philipsen HP. Om keratocyster (kolestetomer) i kaeberne. Tandlaegebledet 1956;60:963.
  • 13 Pýndborg JJ, Hansen J. Studýes on odontogenýc cyst epýthelýum. 2. clýnýcal and roentgenologýc aspects of odontogenýc keratocysts. Acta Pathol Microbiol Scand 1963;58:283-94.
  • 14 Chow HT. Odontogenic keratocyst: A clinical experience in Singapore. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1998;86:573-7.
  • 15 Philipsen HP. Keratocysticodontogenic tumor. In: Barnes L, Eveson JW, Reichart P, Sidranskry D, editors. World Health Organization Classification of Tumours: Pathology and Genetics of Head and Neck Tumours. Lyon: IARC Press; 2005. p. 306-7.
  • 16 Barreto DC, Gomez RS, Bale AE, Boson WL, De Marco L. PTCH gene mutations in odontogenic keratocysts. J Dent Res 2000;79:1418-22.
  • 17 Henley J, Summerlin DJ, Tomich C, Zhang S, Cheng L. Molecular evidence supporting the neoplastic nature of odontogenic keratocyst: A laser capture microdissection study of 15 cases. Histopathology 2005;47:582-6.
  • 18 Zhao YF, Wei JX, Wang SP. Treatment of odontogenic keratocysts: A follow-up of 255 Chinese patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002;94:151-6.
  • 19 Chen CH, Lin CC. Clinical and histopathological study of the odontogenic keratocyst - A follow-up study of 16 cases. Kaohsiung J Med Sci 1986;2:601-7.
  • 20 Oda D, Rivera V, Ghanee N, Kenny EA, Dawson KH. Odontogenic keratocyst: The northwestern USA experience. J Contemp Dent Pract 2000;1:60-74.
  • 21 Stoelinga PJ. Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg 2001;30:14-25.
  • 22 Brannon RB. The odontogenic keratocyst. A clinic opathologic study of 312 cases. Part I. Clinical features. Oral Surg Oral Med Oral Pathol 1976;42:54-72.
  • 23 Blanas N, Freund B, Schwartz M, Furst IM. Systematic review of the treatment and prognosis of the odontogenic keratocyst. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000;90:553-8.
  • 24 Chapelle KA, Stoelinga PJ, de Wilde PC, Brouns JJ, Voorsmit RA. Rational approach to diagnosis and treatment of ameloblastomas and odontogenic keratocysts. Br J Oral Maxillofac Surg 2004;42:381-90.
  • 25 Irvine GH, Bowerman JE. Mandibular keratocysts: Surgical management. Br J Oral Maxillofac Surg 1985;23:204-9.
  • 26 Schmidt BL, Pogrel MA. The use of enucleation and liquid nitrogen cryotherapy in the management of odontogenic keratocysts. J Oral Maxillofac Surg 2001;59:720-5.
  • 27 Stoelinga PJ. Long-term follow-up on keratocysts treated according to a defined protocol. Int J Oral Maxillofac Surg 2001;30:14-25.
  • 28 Bramley P. The odontogenic keratocyst - An approach to treatment. Int J Oral Surg 1974;3:337-41.
  • 29 Meara JG, Li KK, Shah SS, Cunningham MJ. Odontogenic keratocysts in the pediatric population. Arch Otolaryngol Head Neck Surg 1996;122:725-8.