Abstract
Context: Local drug delivery agents. Aims: To clinically evaluate the efficacy of Chlorhexidine chip (PerioCol™ CG) with Tetracycline
fibers (Periodontal Plus AB™). Settings and Design: Randomized controlled, split mouth study design with an observation period of six
months. Materials and Methods: Patients were allocated in 3 experimental treatment groups, Group A: SRP + CHX Chip,
Group B: SRP + Tetracycline fibers, and Group C: SRP alone (control group). 420 bleeding
sites in 35 patients (18 females and 17 males) with chronic periodontitis (5-8mm probing
depth), were evaluated clinically for pocket probing depth (PD), Clinical Attachment
level (CAL), and Bleeding on Probing (BoP). Statistical Analysis:
T-test and CV. Results: All the treatment groups were found to be efficacious as demonstrated by improvement
in PD, CAL, and BoP. In the short term, CHX group showed increased gain of CAL but
on long term observation the Tetracycline fiber group showed better consistent clinical
results in comparison to the other two groups. Conclusions: Group B (SRP + Tetracycline fibers) resulted in better optimum clinical results in
comparison to the other two treatment groups.
Keywords
Chlorhexidine chips - chronic periodontitis - local drug delivery - periodontal pocket
- tetracycline fibers