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CC BY-NC-ND 4.0 · The Arab Journal of Interventional Radiology 2019; 3(01): 15-18
DOI: 10.4103/AJIR.AJIR_37_18
Original Article

Effectiveness of Percutaneous Ethanol Injection Therapy Compared to Parathyroidectomy in the Management of Secondary and Tertiary Hyperparathyroidism

Inmutto Nakarin
Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
,
Srisuwan Tanop
Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
,
Kattipatanapong Thanate
Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
,
Pochan Prach
Department of Radiology, Chiang Mai University, Chiang Mai, Thailand
› Author Affiliations Financial support and sponsorship Nil.
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Background: Secondary hyperparathyroidism (SHPT) and tertiary hyperparathyroidism (THPT) are a common complication of chronic renal failure. Percutaneous ethanol injection therapy (PEIT) has been used as alternative to surgery, but its effectiveness is inconsistent. Objectives: The objective of the study is to evaluate the effectiveness of PEIT in the management of patients with SHPT and THPT. Materials and Methods: Ninety-one patients with chronic renal failure and SHPT or THPT were treated with PEIT (n = 55) and surgery (n = 36) between January 2006 and July 2015. The medical records, imaging studies, and ablation techniques were reviewed to assess the efficacy of each treatment modality and complications. Results: Parathyroid hormone (PTH) level after treatment <160 pg/mL was used to indicate success of treatment. PEIT showed lower effectiveness compared to surgery (1.8% vs. 61.1%). There was no complication in PEIT group. Symptomatic hypocalcemia was found 11.1% in surgery group. Conclusion: PEIT in treatment of secondary and THPT was much less effective than surgery due to large nodule sizes, high levels of PTH, and multiple parathyroid nodules.

Chronic renal failure - percutaneous ethanol injection therapy - secondary hyperparathyroidism - tertiary hyperparathyroidism


Publication History

Article published online:
23 March 2021

© 2019. The Arab Journal of Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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