Metastasis of renal cell carcinoma to urinary bladder: A rare case report with review of literature

Saha Arpita; Jain Manoj; Saha Kaushik; Srivastava Anish

doi:10.4103/JLP.JLP_108_16

Journal of Laboratory Physicians, Table of Contents

CC BY-NC-ND 4.0 · J Lab Physicians 2017; 9(04): 322-324
DOI: 10.4103/JLP.JLP_108_16

Case Report

Metastasis of renal cell carcinoma to urinary bladder: A rare case report with review of literature

Saha Arpita

Department of Pathology, SGPGIMS, Lucknow, Uttar Pradesh, India

,

Jain Manoj

Department of Pathology, SGPGIMS, Lucknow, Uttar Pradesh, India

,

Saha Kaushik

Department of Pathology, SGPGIMS, Lucknow, Uttar Pradesh, India

,

Srivastava Anish

Department of Urology, SGPGIMS, Lucknow, Uttar Pradesh, India

› Author Affiliations

Abstract

PDF Download

Abstract

Metachronous metastatic renal cell carcinoma (RCC) to bladder is rare incidence. We report a case of RCC with metachronous metastasis to the urinary bladder occurring 2 years postradical nephrectomy. In a follow‑up for the past 1 year, the patient is doing well. To the best of our knowledge, this case is the second case of bladder metastasis from RCC in the Indian literature. We reviewed literature and discuss the histopathological features of bladder metastasis of RCC.

Key words

Metachronous - metastatic renal cell carcinoma - urinary bladder

PDF (1684 kb)

References

References
1 Bukowski RM. Natural history and therapy of metastatic renal cell carcinoma: The role of interleukin-2. Cancer 1997;80:1198-220.
2 Eble JN, Sauter G, Epstein JI. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon: IARC Press; 2004.
3 Cronin RE, Kaehny WD, Miller PD, Stables DP, Gabow PA, Ostroy PR, et al. Renal cell carcinoma: Unusual systemic manifestations. Medicine (Baltimore) 1976;55:291-311.
4 Abeshouse BS. Metastasis to ureters and urinary bladder from renal carcinoma; Report of two cases. J Int Coll Surg 1956;25:117-26.
5 Roberts DI. Secondary neoplasms of the genitourinary tract. Br J Urol1978;50:68.
6 Dogra P, Kumar A, Singh A. An unusual case of von hipple lindau (VHL) syndrome with bilateral multicentric renal cell carcinoma with synchronous solitary urinary bladder metastasis. Int Urol Nephrol 2007;39:11-4.
7 Hoffmain EH. Nvpernephrom-metastasen. Dtsch Aled Wschr 1907;33:303.
8 Chinegwundoh FI, Khor T, Leedham PW. Bladder metastasis from renal cell carcinoma. Br J Urol 1997;79:650-1.
9 Gulati M, Gore JL, Pantuck AJ, Kim Y, Barajas L, Rajfer J, et al. Ureteral tumor thrombus from renal cell carcinoma extending into bladder. Urol Oncol 2007;25:393-5.
10 Sim SJ, Ro JY, Ordonez NG, Park YW, Kee KH, Ayala AG, et al. Metastatic renal cell carcinoma to the bladder: A clinicopathologic and immunohistochemical study. Mod Pathol 1999;12:351-5.
11 Raviv S, Eggener SE, Williams DH, Garnett JE, Pins MR, Smith ND, et al. Long-term survival after "drop metastases" of renal cell carcinoma to the bladder. Urology 2002;60:697.
12 Mayer WA, Resnick MJ, Canter D, Ramchandani P, Kutikov A, Harryhill JF, et al. Synchronous metastatic renal cell carcinoma to the genitourinary tract: Two rare case reports and a review of the literature. Can J Urol 2009;16:4611-4.
13 Uygur MC, Ozen HA, Sungur A, Remzi D. A solitary and synchronous metastasis of renal cell carcinoma to the bladder. Int Urol Nephrol 1994;26:529-33.
14 Knez VM, Barrow W, Lucia MS, Wilson S, La Rosa FG. Clear cell urothelial carcinoma of the urinary bladder: A case report and review of the literature. J Med Case Rep 2014;8:275.