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CC BY-NC-ND 4.0 · J Lab Physicians 2018; 10(01): 113-115
DOI: 10.4103/JLP.JLP_114_17
Case Report

Fine-needle aspiration cytology of granulocytic sarcoma presenting as a breast lump – Report of a rare case with a comprehensive literature search

Abhishek Sharma
Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
,
Anjan Kr. Das
Department of Pathology, Calcutta National Medical College, Kolkata, West Bengal, India
,
Subrata Pal
Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
,
Subodh Bhattacharyya
Department of Pathology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
› Author Affiliations Financial support and sponsorship: Nil
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Abstract

Myeloid sarcoma is a neoplasm of myeloid cells that can arise before or concurrent with or may follow acute myeloid leukemia. Very rarely, it can present as an isolated breast lump. We have diagnosed a case of myeloid sarcoma by fine-needle aspiration cytology (FNAC), in a 52-year-old woman who presented with the right-sided breast lump. FNAC showed hypercellular smears with immature myeloid cells few neutrophils and many large round cells with high nuclear-cytoplasmic ratio, prominent nucleoli and a moderate amount of granular cytoplasm. The blast cells were myeloperoxidase positive and complete blood count, and peripheral blood examination were normal. We report this case for its rarity and as a note of caution to a pathologist to consider myeloid sarcoma in the differential diagnosis of breast lump to provide the correct diagnosis and avoid incorrect treatment of a curable disease.

Key words

Acute myeloid leukemia - breast - cytology - myeloid sarcoma


Publication History

Received: 14 June 2017

Accepted: 27 September 2017

Article published online:
19 February 2020

© 2018.

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