Salmonella osteomyelitis: A rare extraintestinal manifestation of an endemic pathogen

Ranjana Rohilla; Mohit Bhatia; Pratima Gupta; Arpana Singh; Ravi Shankar; Balram Ji Omar

doi:10.4103/JLP.JLP_165_18

Journal of Laboratory Physicians, Table of Contents

CC BY-NC-ND 4.0 · J Lab Physicians 2019; 11(02): 164-170
DOI: 10.4103/JLP.JLP_165_18

Case Report

Salmonella osteomyelitis: A rare extraintestinal manifestation of an endemic pathogen

Authors

Ranjana Rohilla

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Mohit Bhatia

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Pratima Gupta

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Arpana Singh

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Ravi Shankar

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India
Balram Ji Omar

Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India

Abstract

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Abstract

Salmonella enterica serovar Typhi and Paratyphi usually cause enteric fever in humans characterized by fever and gastrointestinal symptoms such as diarrhea. Bacteremia is a constant feature of enteric fever, and occasionally, dissemination of bacilli throughout the body results in the establishment of one or more localized foci of persisting infection. This happens especially in patients with preexisting conditions such as hemoglobinopathies, previous joint trauma, surgery, connective tissue diseases, lymphoma, diabetes, alcoholism, immunosuppressive state, and extremes of ages. Rarely, these extraintestinal Salmonella infection cases have also been reported in immunocompetent individuals without any obvious predisposing factors. Salmonella osteomyelitis, a rare sequelae of typhoid, may occur as a result of hematogenous seeding of the bone or joints due to a bacteremic episode. It may also spread from nearby areas of infection or penetrating trauma. Timely diagnosis and treatment of this condition are necessary because if left untreated, it can lead to permanent functional deficits later on. We hereby present a case series with brief review of literature on Salmonella osteomyelitis in immunocompetent patients without any known predisposing conditions over a period of 1 year (2017–2018) from a Tertiary Care Teaching Hospital in Uttarakhand, India.

Key words

Enteric fever - immunocompetent - Salmonella osteomyelitis

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References

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