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CC BY-NC-ND 4.0 · Avicenna J Med 2018; 8(03): 110-113
DOI: 10.4103/ajm.AJM_62_18
CASE REPORT

Aggressive orbital rhabdomyosarcoma in adulthood: A case report in a public hospital in Damascus, Syria

Tagrid Younes Ahmad
Department of Internal Medicine, Tishreen hospital, Damascus, Syria
,
Hasan Nabil Al Houri
Department of Internal Medicine, Al Assad University Hospital and Al Mouwasat University Hospital, Damascus, Syria
,
Abdullah Nabil Al Houri
Department of Internal Medicine, University of Jordan, Amman, Syria
,
Nagham Younes Ahmad
Department of Ophthalmology, Yusuf Al-Azma Hospital, Damascus, Syria
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Orbital rhabdomyosarcoma (RMS) is a highly malignant tumor that originates mainly from mesenchymal tissue. It is considered a rare childhood malignancy; therefore, presentation in adulthood is scarce. In this case report, a 36-year-old male patient presented with a rapidly progressive RMS of the left orbit. The patient was treated in a different institution with radiochemotherapy with good response. However, relapse occurred after 2 months of completing the course, as rapid growing proptosis. Computed tomography scan revealed a lesion in the left orbit with invasion of the left ethmoid cells and the left maxillary sinus. Exenteration of the left orbit with the left partial maxillectomy and ethmoidectomy was performed. RMS is a highly aggressive malignancy that should be considered in any orbital mass that progresses rapidly. Surgery should be the first line in treatment. Delay in diagnosis and inappropriate treatment negatively affects the outcome.

Keywords

Adulthood - oncology - ophthalmology - orbital rhabdomyosarcoma


Publication History

Article published online:
12 August 2021

© 2018. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Ferrari A, Dileo P, Casanova M, Bertulli R, Meazza C, Gandola L. et al. Rhabdomyosarcoma in adults. A retrospective analysis of 171 patients treated at a single institution. Cancer 2003; 98: 571-80
    CrossrefPubMedSearch in Google Scholar
  • 2 Pathology-Rhabdomyosarcoma. Available from: http://www.emedicine.medscape.com/article/873546-overview#a1.[Last accessed on 2018 Jan 1].
  • 3 McDonough RL, Leib ML. Atypical presentation of orbital rhabdomyosarcoma: A report of two cases. J Pediatr Ophthalmol Strabismus 1995; 32: 262-5
    CrossrefPubMedSearch in Google Scholar
  • 4 Young JLJr, Ries LG, Silverberg E, Horm JW, Miller RW. Cancer incidence, survival, and mortality for children younger than age 15 years. Cancer 1986; 58: 598-602
    CrossrefPubMedSearch in Google Scholar
  • 5 Kaliaperumal S, Tiroumal S, Rao V. Orbital rhabdomyosarcoma: A case series. Indian J Cancer 2007; 44: 104-7
    CrossrefPubMedSearch in Google Scholar
  • 6 Lavaju P, Das H, Malla P, Tiwari A, Sinha A, Upadhyaya O. et al. Orbital rhabdomyosarcoma in an adult. Nepal J Ophthalmol 2010; 2: 64-7
    CrossrefPubMedSearch in Google Scholar
  • 7 Garduño-Vieyra L, Hernandez-Da Mota SE, Gonzalez CR, Gamez-Carrillo R. et al. Rhabdomyosarcoma in an elderly patient. A case report. Rev Mex Oftalmol 2017; 91: 73
    Search in Google Scholar
  • 8 Frayer WC, Enterline HT. Embryonal rhabdomyosarcoma of the orbit in children and young adults. AMA Arch Ophthalmol 1959; 62: 203-10
    CrossrefPubMedSearch in Google Scholar
  • 9 Ashton N, Morgan G. Embryonal sarcoma and embryonal rhabdomyosarcoma of the orbit. Journal of Clinical Pathology 1965; 18: 699-714
    CrossrefPubMedSearch in Google Scholar
  • 10 Jurdy L, Merks JH, Pieters BR, Mourits MP, Kloos RJ, Strackee SD. et al. Orbital rhabdomyosarcomas: A review. Saudi J Ophthalmol 2013; 27: 167-75
    CrossrefPubMedSearch in Google Scholar