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CC BY-NC-ND 4.0 · Avicenna J Med 2020; 10(04): 189-197
DOI: 10.4103/ajm.ajm_175_20
Original Article

A systematic review of contemporary evidence on SARS-CoV-2 and HIV coinfection: What does it look like up to date?

Mohammad Abrar Shareef
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Hafss M Bashaiwth
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Abdullah O AlAkbari
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Marwan S Bahamran
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Maryam O AlAmodi
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Salem H Albaiti
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Meryam A Ali
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Abdulaziz M Eshaq
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Khaled Alkattan
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
,
Abdulhadi A Alamodi
Department of Family Medicine, Sebasticook Valley Hospital, Pittsfield, Maine, USA
› Author Affiliations
Subject Editor: Financial support and sponsorship Nil.
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Abstract

Background: Preexisting alteration of the immune system by factors including older age, cardiovascular diseases, morbid obesity, diabetes, and chronic obstructive pulmonary disease (COPD) have detrimental effects on SARS-CoV-2 patients. Literature regarding SARS-CoV-2/human immunodeficiency virus (HIV) is still developing. Materials and Methods: We reviewed the existing literature pertaining to SARS-CoV-2/HIV coinfection systematically. Research records’ characteristics and patients’ clinical data were collected. Results: Seven research records were included, of which three were case series and four were case reports, reporting a total of 16 cases. There was one case of death, whereas (15/16) patients were discharged home. Majority of patients developed consistent clinical presentation of SARS-CoV-2. All patients had initial positive RT-PCR results, and four cases had HIV-related lymphopenia. Conclusion: Although the current literature is still growing to increase our understanding of SARS-CoV-2/HIV coinfection, people living with HIV should adhere to the guidelines of healthy behavior and practice during this pandemic.

Keywords

Coinfection - COVID-19 - HIV - review - SARS-CoV-2


Publication History

Article published online:
04 August 2021

© 2020. Syrian American Medical Society. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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