Abstract
Background: The irrational use of antibiotics is a global issue and it can lead to morbidity,
mortality, and increased health care costs. Hence, proper use of antibiotics is imperative
and should be included in the pharmaceutical care plan. Objective: The objective of this study was to evaluate the prescribing pattern of antibiotics
for children using WHO core prescribing indicators. Materials and Methods: A prospective, observational study was carried for 6 months in the pediatric department
at a tertiary care hospital, Pune. The WHO prescribing indicators were used to evaluate
the prescriptions, and the ideal WHO range was considered as a determining factor
for rational prescription. Results: A total of 302 patients were included in the study, with a mean patient age of 4.92
± 4 years. The average number of drugs per encounter was 6.12 (WHO standard is less
than 2). The percentage of antibiotics prescribed was 26.3% with an average of 1.63
antibiotics per prescription. Of the 493 antibiotics, 85.59% were injectable which
is higher than the WHO standard of 13.4–24.1%. A near-optimal value of 99.59% antibiotics
was prescribed from the hospital formulary which is similar to WHO standards, and
the antibiotics prescribed with generic names were 25.76%. The most common class of
antibiotics prescribed were cephalosporins and penicillins. Conclusion: Polypharmacy, high injectable use, and non-adherence to generic prescription were
common in our tertiary care center. Continuous audits, training, and new treatment
protocols are recommended.
Keywords
Antibiotics - pediatrics - rational prescribing - prescribing pattern - WHO prescribing
indicators
