Extensive en plaque intradural extramedullary tuberculomas can occur as a paradoxical
response to chemotherapy for intracranial tuberculomas. We report a case of 31-year-old
male who presented with backache and progressive weakness and urgency of micturition.
Magnetic resonance imaging dorsolumbar spine which showed an ill-defined T1 hypointense
and T2 heterointense lesion noted posterior to the thoracic spinal cord, extending
from C7 to D5 vertebral levels suggestive of en plaque meningioma. The patient underwent
D1-D5 laminectomy, with subtotal debulking of the tumor. The histopathological examination
of lesion was suggestive of granulomatous inflammation with multinucleated and Langhan
type giant cells confirming the diagnosis of tuberculoma.
Key-words:
En plaque meningioma - en plaque tuberculoma - paradoxical response introduction tuberculosis
