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CC BY-NC-ND 4.0 · Asian J Neurosurg 2021; 16(04): 841-845
DOI: 10.4103/ajns.AJNS_116_21
Case Report

A true mimicker to plasmacytoma clinically, radiologically, and pathologically – A rare case report

Shino Ashly
Department of Neurosurgery, Indo American Hospital, Vaikom, Kerala
,
Anu Thomas
Department of Neurosurgery, Indo American Hospital, Vaikom, Kerala
,
Sajeev Vadakkedam
Department of Neurosurgery, Indo American Hospital, Vaikom, Kerala
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Lympho plasmacytoma is distinct type of diffuse large B cell lymphoma predominantly seen in HIV-positive patients. The diagnosis of lympho plasmacytoma could be a challenge due to its overlapping characterizes with those of myeloma and lymphoma. We report a case of a 50-year-old man who initially presented with a painful solitary destructive lesion at the second lumbar vertebra. Clinico-pathological findings were consistent with a solitary plasmacytoma, and he was treated with definitive radiotherapy. Eight months after completing radiotherapy, he was found to have similar lesions at D4 vertebral body, multiple ribs, and pelvis. Subsequent biopsy confirmed lympho plasmacytoma. Because of its rarity and heterogeneous presentations, lympho plasmacytoma could easily be overlooked clinically and pathologically in immunocompetent patients. The diagnosis of lympho plasmacytoma should be considered when there is coexpression of myeloma and lymphoma immune markers.

Key-words:

Lympho plasmacytoma - lymphoma - myeloma - solitary plasmacytoma

Financial support and sponsorship

Nil.




Publikationsverlauf

Eingereicht: 17. März 2021

Angenommen: 16. Juli 2021

Artikel online veröffentlicht:
16. August 2022

© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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