Extraaxial cerebellopontine angle medulloblastoma with multiple intracranial metastases in adult: A rare case report with a review of literature

Saraj Singh; Niraj Kumar

doi:10.4103/ajns.AJNS_120_20

Asian Journal of Neurosurgery, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(03): 695-698
DOI: 10.4103/ajns.AJNS_120_20

Case Report

Extraaxial cerebellopontine angle medulloblastoma with multiple intracranial metastases in adult: A rare case report with a review of literature

Saraj Singh

Department of Neurosurgery, AIIMS, Patna, Bihar

,

Niraj Kumar

¹Department of Neurology, AIIMS, Rishikesh, Uttarakhand

› Institutsangaben

Abstract

Medulloblastoma (MB) is very rare malignant primary brain tumor in adults and its location at cerebellopontine angle (CPA) is even rarer. There are only few case reports of CPA MBs in literature. Most of them are reported in pediatric age groups which are mostly intraaxial. Only 11 cases of extra-axial CPA MBs have been reported so far. The author is reporting a very rare case of adult extra-axial CPA MBs with multiple intracranial metastases. We are also reviewing clinical and radiological features and unusual way of its presentation along with surgical management. Keeping MBs as one of the differential diagnosis for extra-axial CPA tumors is going to increase our spectrum of diagnosis which can lead to alteration in management.

Key-words:

Cerebello-pontine angle - extra-axial - medulloblastoma - metastases

Volltext

Referenzen

References
1 Chern JJ, Rao G, Lang FF, Medulloblastoma. In: Youmans JR, editor. Neurological Surgery. 7th ed.., Vol. 2. Philadelphia, PA W.B: Saunders Company; 2011. p. 549.
2 Bhaskar MK, Jaiswal M, Ojha BK, Singh SK, Chandra A, Meel M, et al. Extra-Axial Cerebellopontine Angle Medulloblastoma in an Infant. Pediatr Neurosurg 2017;52:122-6.
3 Goudihalli SR, Pathak A, Brar R, Mundi I. Reappraisal of cerebellopontine angle medulloblastomas: Report of a fatal case and lessons learned. Interdisciplinary Neurosurg 2018;12:20-23.
4 Presutto E, Chappell M, Fullmer J, Ezhapilli S. Posterior fossa medulloblastoma in an atypical extra-axial location: A case report. Radiol Case Rep 2018;13:365-70.
5 Bahrami E, Bakhti S, Fereshtehnejad SM, Parvaresh M, Khani MR. Extra-axial medulloblastoma in cerebello-pontine angle: A report of a rare case with literature review. Med J Islam Repub Iran 2014;28:57.
6 Singh M, Cugati G, Symss NP, Pande A, Vasudevan MC, Ramamurthi R. Extra axial adult cerebellopontine angle medulloblastoma: An extremely rare site of tumor with metastasis. Surg Neurol Int 2011;2:25.
7 Fallah A, Banglawala SM, Provias J, Jha NK. Extra-axial medulloblastoma in the cerebellopontine angle. Can J Surg 2009;52:E101-E102.
8 Pant I, Chaturvedi S, Gautam VK, Pandey P, Kumari R. Extra-axial medulloblastoma in the cerebellopontine angle: Report of a rare entity with review of literature. J Pediatr Neurosci 2016;11:331-4.
9 Akay KM, Erdogan E, Izci Y, Kaya A, Timurkaynak E. Medulloblastoma of the cerebellopontine angle-case report. Neurol Med Chir (Tokyo) 2003;43:555-8.
10 McCarthy C, Hofer M, Vlychou M, Khundkar R, Critchley P, Cudlip S, et al. Metastatic meningioma presenting as a malignant soft tissue tumour. Clin Sarcoma Res 2016;6:23.
11 Martin AM, Raabe E, Eberhart C, Cohen KJ. Management of pediatric and adult patients with medulloblastoma. Curr Treat Options Oncol 2014;15:581-94.
12 Tabori U, Sung L, Hukin J, Laperriere N, Crooks B, Carret AS, et al. Canadian Pediatric Brain Tumor Consortium. Medulloblastoma in the second decade of life: A specific group with respect to toxicity and management: A Canadian pediatric brain tumor consortium Study. Cancer 2005;103:1874-80.
13 Martin AM, Raabe E, Eberhart C, Cohen KJ. Management of pediatric and adult patients with medulloblastoma. Curr Treat Options Oncol 2014;15:581-594. doi:10.1007/s11864-014-0306-4.
14 Nalita N, Ratanalert S, Kanjanapradit K, Chotsampancharoen T, Tunthanathip T. Survival and prognostic factors in pediatric patients with medulloblastoma in Southern Thailand. J Pediatr Neurosci 2018;13:150-7.
15 Ibis K, Karadeniz A, Meral R, Guveli M, Basaran M, Bavbek S, et al. The prognostic factors and outcome of adult medulloblastoma: Where we stand. Int Surg 2016;101:352-60.
16 Rutkowski S, von Hoff K, Emser A, Zwiener I, Pietsch T, Figarella-Branger D, et al. Survival and prognostic factors of early childhood medulloblastoma: An international meta-analysis. J Clin Oncol 2010;28:4961-8.
17 Chan AW, Tarbell NJ, Black PM, Louis DN, Frosch MP, Ancukiewicz M, et al. Adult medullolastoma: Prognostic factors and patterns of relapse. Neurosurgery 200;47:623-31.
18 Carrie C, Lasset C, Alapetite C, Haie-Meder C, Hoffstetter S, Demaille MC, et al. Multivariate analysis of prognostic factors in adult patients with medulloblastoma. Cancer 1994;74:2352-60.
19 Skolyszewski J, Glinski B. Results of postoperative irradiation of medulloblastoma in adults. Int J Radiat Oncol Biol Phys 1989;16:479-82.
20 Boiardi A, Silvani A, Eoli M, Lamperti E, Salmaggi A, Gaviani P, et al. Embryonal tumors in the adult population: Implications in therapeutic planning. Neurol Sci 2000;21:23-30.