Objectives: The primary lymphoma of the central nervous system is a cancer rare. The
diagnosis of this tumoral entity must be considered as an emergency considering the
therapeutical involved. Therefore, we report this entity while reporting diagnostic
challenges. Patients and Methods: Unfortunately, the conventional clinical and imaging
signs can be confusing and might contribute to delay the diagnosis process of potentially
curable pathological entity. The diagnosis confirmation in immunocompetent patients
is based on a stereotaxic biopsy. Results and Conclusion: In this paper, we report
a case illustrating the contribution of multimodal imaging including diffusion-weighted
magnetic resonance imaging (MRI), diffusion tensor MRI, perfusion MRI, and proton
MR spectroscopy to the diagnostic approach of the atypical primary lymphoma of the
central nervous system.
Key-words:
Intraparenchymal tumor - multimodal imaging - primary brain lymphoma