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CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(01): 175-180
DOI: 10.4103/ajns.AJNS_137_18
Original Article

Venture in 101 cranial punctures: A comparative study between frame-based versus frameless biopsy of 101 intracranial space occupying lesion

Suresh Bishokarma
Department of Neurosurgery, National Institute of Neurological and Allied Sciences, Kathmandu
,
Pratyush Shrestha
Department of Neurosurgery, National Institute of Neurological and Allied Sciences, Kathmandu
,
Sagar Koirala
Department of Neurosurgery, National Institute of Neurological and Allied Sciences, Kathmandu
,
Manita Raut
Department of Neurosurgery, National Institute of Neurological and Allied Sciences, Kathmandu
,
Dinesh Gongal
Department of Neurosurgery, National Institute of Neurological and Allied Sciences, Kathmandu
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Background: Presumptive diagnosis based solely on the clinical picture and imaging is not sufficient to provide appropriate treatment with certainty and hence histopathological confirmation of intracranial space occupying lesion (ICSOL) is essential. Needle biopsy via stereotactic frame-based or frameless neuronavigation technique is efficient procedure. The objective of this study is to compare their accuracy and efficacy and safety. Methods: This is a retrospective comparative study conducted among 101 biopsies of ICSOL. Patients data were retrieved from medical record. Data were analyzed in SPSS ver. 20. P value of <0.05 was considered significant. Results: Out of 101 patients, Frame-based stereotactic biopsy was done among 55 patients (54.4%) while 46 patients (45.6%) underwent frameless stealth neuronavigation guided biopsy. Male to female ration was 2.1:1. Age ranged from 5 to 82 years. 54.5% (55 patients) have deeper location of tumor while 45.5% (46 patients) have lobar location of tumor. Frontal (16.8%) and Thalamic (13.8%) were the common site. Mean size of tumor was 3.09±0.85cms. There was statistically significant difference in operative duration among study groups. Overall Diagnostic yield was 89.1%. Glioma was the most common (50.5%) diagnosis. Glioblastoma WHO Grade IV was 37.6% followed by lymphoma (12.8%). Conclusion: Needle biopsy via stereotactic frame-based or neuronavigation frameless technique is a safe and efficient procedure having high diagnostic yield. Reasons for negative biopsy could be missed target or retrieval of gliotic tissue.

Key-words:

Biopsy - brain lesion - frame-based - frameless - neuronavigation - accuracy

Financial support and sponsorship

Nil.




Publication History

Article published online:
09 September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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