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CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(04): 1027-1030
DOI: 10.4103/ajns.AJNS_174_20
Case Report

An unusual case of primary intracranial germinoma with diffuse subarachnoid spread masquerading as tuberculous meningitis

Amit Sharma
Department of Neurosurgery, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi
,
Anita Jagetia
Department of Neurosurgery, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi
,
Arvind Srivastava
Department of Neurosurgery, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi
,
Ravindra Saran
1   Department of Pathology, Govind Ballabh Pant Institute of Postgraduate Medical Education and Research, New Delhi
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Central nervous system (CNS) germinomas often extend or disseminate into the ventricular and subarachnoid space. We present a case of primary CNS germinoma consisting mainly of meningeal dissemination, which is extremely unusual and must be kept in the differential diagnosis.

Key-words:

Germinoma - subarachnoid dissemination - tubercular meningitis

Financial support and sponsorship

Nil.




Publication History

Received: 26 May 2020

Accepted: 24 July 2020

Article published online:
16 August 2022

© 2020. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Jennings MT, Gelman R, Hochberg F. Intracranial germ-cell tumors: Natural history and pathogenesis. J Neurosurg 1985;63:155-67.
  • 2 Phi JH, Cho BK, Kim SK, Paeng JC, Kim IO, Kim IH, et al. Germinomas in the basal ganglia: Magnetic resonance imaging classification and the prognosis. J Neurooncol 2010;99:227-36.
  • 3 Hong SW, Choi HY, Koh EJ. Surgery of the Tumors in the Ventricular System. J Korean Neurosurg Soc 2006;39:26-31.
  • 4 Shono T, Natori Y, Morioka T, Torisu R, Mizoguchi M, Nagata S, et al. Results of a long-term follow-up after neuroendoscopic biopsy procedure and third ventriculostomy in patients with intracranial germinomas. J Neurosurg 2007;107:193-8.
  • 5 Yip CM, Hsu SS, Liao WC, Chen JY, Liu SH, Chen CH. Neuroendoscopic management of intraventricular germinoma at the foramen of Monro: Case report and review of the literature. Minim Invasive Neurosurg 2011;54:191-5.
  • 6 Onuma K, Ishikawa E, Matsuda M, Shibata Y, Satomi K, Yamamoto T, et al. Navigation-guided endoscopic biopsy for pathological diagnosis for intraparenchymal pure germinoma near the ventricular trigone. Surg Neurol Int 2012;3:9.
  • 7 Ghosh PS, Tekautz T, Mitra S. Pearls and Oysters: Bifocal germinoma of the brain: Review of systems is key to the diagnosis. Neurology 2012;78:e8-10.
  • 8 Reisch N, Kühne-Eversmann L, Franke D, Beuschlein F, Mueller-Lisse UG, Reincke M, et al. Intracranial germinoma as a very rare cause of panhypopituitarism in a 23-year old man. Exp Clin Endocrinol Diabetes 2009;117:320-3.
  • 9 Suresh TN, Mahadevan A, Santosh V, Shankar SK. Subarachnoid spread of germinoma mimicking tuberculous meningitis. Neurol India 2004;52:251-3.