CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(02): 487-490
DOI: 10.4103/ajns.AJNS_278_18
Original Article

Hydrocephalus after gamma knife radiosurgery for schwannoma

Yu Shimizu
1   Department of Neurosurgery, Kanazawa Medical Center, Kanazawa
2   Department of Neurosurgery, Toyama City Hospital, Toyama
,
Tadao Miyamori
2   Department of Neurosurgery, Toyama City Hospital, Toyama
,
Jun Yamano
2   Department of Neurosurgery, Toyama City Hospital, Toyama
› Institutsangaben

Objective: Gamma Knife radiosurgery (GKRS) has been established as an effective and safe treatment for intracranial Schwannoma. However, communicating hydrocephalus can occur after GKRS. The risk factors of this disorder are not yet fully understood. The objective of the study was to assess potential risk factors for hydrocephalus after GKRS. Methods: We retrospectively reviewed the medical radiosurgical records of 92 patients who underwent GKRS to treat intracranial Schwannoma and developed communicating hydrocephalus. The following parameters were analyzed as potential risk factors for hydrocephalus after GKRS: age, sex, target volume, irradiation dose, prior tumor resection, treatment technique, tumor enhancement pattern, and protein level of cerebrospinal fluid (CSF) after GKRS. Results: Of the 92 patients, eight of them developed communicating hydrocephalus. Target volume and tumor enhancement pattern, and protein level of CSF ware associated with the development of hydrocephalus. Conclusion: In particular, patients with intracranial Schwannomas with large tumor size, ring enhancement patterns, and high protein level of CSF should be carefully observed.

Financial support and sponsorship

Nil.




Publikationsverlauf

Artikel online veröffentlicht:
09. September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Samii M, Matthies C. Management of 1000 vestibular schwannomas (acoustic neuromas): The facial nerve--preservation and restitution of function. Neurosurgery 1997;40:684-94.
  • 2 Park CK, Lee SH, Choi MK, Choi SK, Park BJ, Lim YJ, et al. Communicating hydrocephalus associated with intracranial schwannoma treated by gamma knife radiosurgery. World Neurosurg 2016;89:593-600.
  • 3 Flickinger JC, Kondziolka D, Niranjan A, Lunsford LD. Results of acoustic neuroma radiosurgery: An analysis of 5 years' experience using current methods. J Neurosurg 2001;94:1-6.
  • 4 Hasegawa T, Kida Y, Kobayashi T, Yoshimoto M, Mori Y, Yoshida J, et al. Long-term outcomes in patients with vestibular schwannomas treated using gamma knife surgery: 10-year follow up. J Neurosurg 2005;102:10-6.
  • 5 Pollock BE, Foote RL, Stafford SL. Stereotactic radiosurgery: The preferred management for patients with nonvestibular schwannomas? Int J Radiat Oncol Biol Phys 2002;52:1002-7.
  • 6 Roche PH, Khalil M, Soumare O, Régis J. Hydrocephalus and vestibular schwannomas: Considerations about the impact of gamma knife radiosurgery. Prog Neurol Surg 2008;21:200-6.
  • 7 Rogg JM, Ahn SH, Tung GA, Reinert SE, Norén G. Prevalence of hydrocephalus in 157 patients with vestibular schwannoma. Neuroradiology 2005;47:344-51.
  • 8 Jeon CJ, Kong DS, Nam DH, Lee JI, Park K, Kim JH, et al. Communicating hydrocephalus associated with surgery or radiosurgery for vestibular schwannoma. J Clin Neurosci 2010;17:862-4.
  • 9 Fukuda M, Oishi M, Kawaguchi T, Watanabe M, Takao T, Tanaka R, et al. Etiopathological factors related to hydrocephalus associated with vestibular schwannoma. Neurosurgery 2007;61:1186-92.
  • 10 Pirouzmand F, Tator CH, Rutka J. Management of hydrocephalus associated with vestibular schwannoma and other cerebellopontine angle tumors. Neurosurgery 2001;48:1246-53.
  • 11 Pollock BE, Driscoll CL, Foote RL, Link MJ, Gorman DA, Bauch CD, et al. Patient outcomes after vestibular schwannoma management: A prospective comparison of microsurgical resection and stereotactic radiosurgery. Neurosurgery 2006;59:77-85.
  • 12 Bloch J, Vernet O, Aubé M, Villemure JG. Non-obstructive hydrocephalus associated with intracranial schwannomas: Hyperproteinorrhachia as an etiopathological factor? Acta Neurochir (Wien) 2003;145:73-8.
  • 13 Hasegawa T, Fujitani S, Katsumata S, Kida Y, Yoshimoto M, Koike J, et al. Stereotactic radiosurgery for vestibular schwannomas: Analysis of 317 patients followed more than 5 years. Neurosurgery 2005;57:257-65.
  • 14 Régis J, Pellet W, Delsanti C, Dufour H, Roche PH, Thomassin JM, et al. Functional outcome after gamma knife surgery or microsurgery for vestibular schwannomas. J Neurosurg 2002;97:1091-100.
  • 15 Norén G. Long-term complications following gamma knife radiosurgery of vestibular schwannomas. Stereotact Funct Neurosurg 1998;70 Suppl 1:65-73.
  • 16 Cauley KA, Ratkovits B, Braff SP, Linnell G. Communicating hydrocephalus after gamma knife radiosurgery for vestibular schwannoma: An MR imaging study. AJNR Am J Neuroradiol 2009;30:992-4.
  • 17 Sawamura Y, Shirato H, Sakamoto T, Aoyama H, Suzuki K, Onimaru R, et al. Management of vestibular schwannoma by fractionated stereotactic radiotherapy and associated cerebrospinal fluid malabsorption. J Neurosurg 2003;99:685-92.
  • 18 Lee S, Seo SW, Hwang J, Seol HJ, Nam DH, Lee JI, et al. Analysis of risk factors to predict communicating hydrocephalus following gamma knife radiosurgery for intracranial schwannoma. Cancer Med 2016;5:3615-21.
  • 19 Nagano O, Higuchi Y, Serizawa T, Ono J, Matsuda S, Yamakami I, et al. Transient expansion of vestibular schwannoma following stereotactic radiosurgery. J Neurosurg 2008;109:811-6.
  • 20 Tanaka Y, Kobayashi S, Hongo K, Tada T, Sato A, Takasuna H, et al. Clinical and neuroimaging characteristics of hydrocephalus associated with vestibular schwannoma. J Neurosurg 2003;98:1188-93.