Spontaneous radiographic disappearance of cerebral aneurysms is often observed under
special conditions such as giant aneurysms. However, spontaneous disappearance of
an unruptured and nongiant intracranial saccular aneurysms is rare. We describe two
cases of this rare vascular phenomenon. The first patient is a 64-year-old female
diagnosed with a small unruptured aneurysm arising from the distal anterior cerebral
artery. Spontaneous disappearance of the aneurysm on magnetic resonance angiography
(MRA) was observed 5 years after the initial diagnosis. Continuous imaging surveillance
also revealed spontaneous reappearance of the aneurysm 2 years later. The second patient
is a 57-year-old female harboring a small unruptured saccular aneurysm arising from
the M1–M2 bifurcation of the middle cerebral artery. The aneurysm showed spontaneous
disappearance on MRA 13 years after the initial diagnosis. These cases provide a new
insight into this natural dynamic process even in cases of a small unruptured intracranial
saccular aneurysm.
Key-words:
Spontaneous disappearance - thrombosis - unruptured cerebral aneurysm