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CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(02): 499-505
DOI: 10.4103/ajns.AJNS_294_18
Original Article

Treatment outcomes of cerebral aneurysms presenting with optic neuropathy: A retrospective case series

Koji Hirata
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Yoshiro Ito
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Wataro Tsuruta
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
2   Department of Neuro-Endovascular Therapy, Toranomon Hospital, Minato, Tokyo
,
Tomoji Takigawa
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
3   Department of Neurosurgery, Saitama Medical Center, Dokkyo Medical University, Koshigaya, Saitama
,
Aiki Marushima
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Masayuki Sato
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
2   Department of Neuro-Endovascular Therapy, Toranomon Hospital, Minato, Tokyo
,
Mikito Hayakawa
4   Department of Neurosurgery, Division for Stroke, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Yasunobu Nakai
5   Department of Neurosurgery, Tsukuba Medical Center Hospital, Tsukuba
,
Noriyuki Kato
6   Department of Neurosurgery, National Hospital Organization Mito Medical Center, Mito, Ibaraki
,
Kazuya Uemura
5   Department of Neurosurgery, Tsukuba Medical Center Hospital, Tsukuba
,
Kensuke Suzuki
3   Department of Neurosurgery, Saitama Medical Center, Dokkyo Medical University, Koshigaya, Saitama
,
Yuji Matsumaru
2   Department of Neuro-Endovascular Therapy, Toranomon Hospital, Minato, Tokyo
4   Department of Neurosurgery, Division for Stroke, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Akio Hyodo
3   Department of Neurosurgery, Saitama Medical Center, Dokkyo Medical University, Koshigaya, Saitama
,
Eiichi Ishikawa
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
,
Akira Matsumura
1   Department of Neurosurgery, Faculty of Medicine, University of Tsukuba, Tsukuba
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Background: Optic neuropathy due to an aneurysm is relatively rare, with only a few small case series on this topic, and no randomized trials having been published until now. As such, the functional prognosis and treatment for aneurysm-induced optic neuropathy remain controversial. Objective: We quantified optic nerve injuries using an objective index (the visual impairment score) and evaluated prognostic factors of postoperative visual function. Materials and Methods: Of 960 patients treated for an unruptured intracranial aneurysm, 18 (1.9%) patients had optic neuropathy. Visual acuity and visual field were assessed before surgery and 6 months' postoperatively. Cases were classified on the basis of treatment modality (coil embolization or flow alteration [FA]) and prognostic factors of the two treatment groups. Results: Of the 18 patients with an intracranial aneurysm and optic neuropathy, 12 (67%) were treated using coil embolization and 6 (33%) were FA. Visual function improved after surgery in 8 patients (44%), 5 (42%) in the coil embolization group, and 3 (50%) in the FA group. The visual function remained stable after surgery in 6 (33%) patients and worsened in 4 (22%). Patients with an aneurysms <15 mm in size had a favorable outcome (P = 0.05). Conclusions: Surgical treatment improved vision in 44% of cases, with no difference in the prognosis of coil embolization and FA and no effect of the duration of symptoms on outcomes. Further, the prognosis of visual function recovery was better for aneurysms <15 mm in diameter.

Key-words:

Coil embolization - intracranial aneurysm - optic nerve neuropathy - parent artery occlusion - visual impairment score

Financial support and sponsorship

Nil.




Publication History

Article published online:
09 September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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