Racial disparities in the incidence and survival of spinal meningioma

Mahmoud Dibas; Ahmad Rajab; Mohammad Atiah; Saadi Aljundi; Sherief Ghozy; Kevin Phan; Nazmus Saquib

doi:10.4103/ajns.AJNS_306_20

Asian Journal of Neurosurgery, Table of Contents

CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(04): 877-881
DOI: 10.4103/ajns.AJNS_306_20

Original Article

Racial disparities in the incidence and survival of spinal meningioma

Mahmoud Dibas

College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah

,

Ahmad Rajab

College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah

,

Mohammad Atiah

College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah

,

Saadi Aljundi

College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah

,

Sherief Ghozy

¹Department of Neurosurgery, El Sheikh Zayed Specialized Hospital, Giza

,

Kevin Phan

²Neurospine Surgery Research Group, Prince of Wales Private Hospital, Sydney, New South Wales

,

Nazmus Saquib

College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah

› Author Affiliations

Abstract

Objective: Race is a significant prognostic factor in various cancers, including the breast. Its prognostic association with spinal meningioma has not been established, although the incidence of spinal meningioma varies by race. In this retrospective cohort study, we aimed to investigate the association of race with the incidence and survival of spinal meningioma among a large population sample. Materials and Methods: A comprehensive search was done in the surveillance, epidemiology, and end results database between 2000 and 2016 to identify patients with spinal meningioma. Overall and race-specific incidence were calculated. The effect of race on overall survival among these patients was determined with Kaplan–Meier curve and Cox proportional hazard models. Results: Of 3502 spinal meningioma patients, 82.6% were Caucasian, 7.7% were African-American, 8.8% were Asian/Pacific Islander and 0.7% were American Indian/Alaska Native. The overall age-adjusted incidence was 0.239/100,000; it was highest among Caucasian (0.249) and lowest among American Indian/Alaska Native patients (0.137). There was a race effect in overall survival in the unadjusted analysis with the worst overall survival reported for Caucasian patients, and the best reported for American Indian/Alaska Native patients. However, this relationship was insignificant in the adjusted analysis. Conclusions: Race was not significantly associated with overall survival among these patients. Future studies should use spinal-meningioma-specific survival as outcome to see whether there is a racial difference in survival.

Key-words:

Incidence - race - spinal meningioma - survival

Full Text

References

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