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CC BY-NC-ND 4.0 · Asian J Neurosurg 2020; 15(04): 877-881
DOI: 10.4103/ajns.AJNS_306_20
Original Article

Racial disparities in the incidence and survival of spinal meningioma

Mahmoud Dibas
College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah
,
Ahmad Rajab
College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah
,
Mohammad Atiah
College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah
,
Saadi Aljundi
College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah
,
Sherief Ghozy
1   Department of Neurosurgery, El Sheikh Zayed Specialized Hospital, Giza
,
Kevin Phan
2   Neurospine Surgery Research Group, Prince of Wales Private Hospital, Sydney, New South Wales
,
Nazmus Saquib
College of Medicine, Sulaiman Al Rajhi University, Al Bukayriyah
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Objective: Race is a significant prognostic factor in various cancers, including the breast. Its prognostic association with spinal meningioma has not been established, although the incidence of spinal meningioma varies by race. In this retrospective cohort study, we aimed to investigate the association of race with the incidence and survival of spinal meningioma among a large population sample. Materials and Methods: A comprehensive search was done in the surveillance, epidemiology, and end results database between 2000 and 2016 to identify patients with spinal meningioma. Overall and race-specific incidence were calculated. The effect of race on overall survival among these patients was determined with Kaplan–Meier curve and Cox proportional hazard models. Results: Of 3502 spinal meningioma patients, 82.6% were Caucasian, 7.7% were African-American, 8.8% were Asian/Pacific Islander and 0.7% were American Indian/Alaska Native. The overall age-adjusted incidence was 0.239/100,000; it was highest among Caucasian (0.249) and lowest among American Indian/Alaska Native patients (0.137). There was a race effect in overall survival in the unadjusted analysis with the worst overall survival reported for Caucasian patients, and the best reported for American Indian/Alaska Native patients. However, this relationship was insignificant in the adjusted analysis. Conclusions: Race was not significantly associated with overall survival among these patients. Future studies should use spinal-meningioma-specific survival as outcome to see whether there is a racial difference in survival.

Key-words:

Incidence - race - spinal meningioma - survival

Financial support and sponsorship

This work was supported by Sulaiman Al Rajhi University, Saudi Arabia, but it had no role in the study design, the collection, analysis, or interpretation of data, in the writing of the report, or in the decision to submit the article for publication.




Publication History

Received: 20 June 2020

Accepted: 07 August 2020

Article published online:
16 August 2022

© 2020. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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