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CC BY-NC-ND 4.0 · Asian J Neurosurg 2019; 14(04): 1291-1294
DOI: 10.4103/ajns.AJNS_53_19
Case Report

Primary pineal rhabdomyosarcoma: A rare case

Mihir Vaidya
0   Department of Neuropathology, Seth G.S.M.C, Mumbai, Maharashtra
,
Asha Shenoy
1   Department of Pathology, Seth G.S.M.C, Mumbai, Maharashtra
,
Naina Goel
1   Department of Pathology, Seth G.S.M.C, Mumbai, Maharashtra
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Primary pineal rhabdomyosarcoma (RMS) is extremely rare, and only three cases have been reported so far. Here, we report a case of 12-year-old male who presented with complaints of diplopia and diminution of vision since 15 days. He also had left-sided facial paresis. Magnetic resonance imaging brain revealed a space-occupying lesion in the region of pineal gland. The patient underwent midline suboccipital craniectomy with excision of tumor. Microscopic examination revealed a highly cellular tumor with areas showing small round cells admixed with cells having abundant eosinophilic cytoplasm resembling rhabdomyoblasts and multinucleated giant cells. Differential diagnoses of pineal anlage tumor and primary RMS were considered. The tumor cells were positive for desmin while being negative for synaptophysin and glial fibrillary acidic protein. Myogenin was used to confirm the diagnosis of RMS, which showed focal nuclear positivity. INI1 was retained. All the markers for germ cell tumors were negative.

Key-words:

Desmin - myogenin - pineal gland - rhabdomyosarcoma

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Publication History

Article published online:
09 September 2022

© 2019. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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