Purpose: Central nervous system (CNS) cancers rank as the most frequent solid tumors and the
leading cause of cancer-related deaths in children and adolescents. There is less
information available about pediatric brain and CNS tumors in low-income and middle-income
countries, suggesting a lack of surgical accessibility or limited capacity to treat
these conditions. In this study, we chose to study the epidemiology of CNS cancers
in the Democratic People's Republic of Korea (DPRK). Methods: We extracted the prevalence, incidence, deaths, and disability-adjusted life years
(DALYs) associated with CNS cancers in individuals under the age of 20 from the 2017
Global Burden of Disease study from the Institute for Health Metrics and Evaluation.
DALYs, which signify the number of healthy life years lost due to ill health, disability,
or early death. Economic impact was calculated from DALYs. Conclusions: Given the large burden of brain and CNS cancers among all pediatric cancers in the
DPRK, scaling up and strengthening surgical services for children is an essential
component to improving care of pediatric CNS cancers in the DPRK. Childhood cancers
are time sensitive, and early diagnosis and treatment are vital in ensuring improved
survival for the vulnerable pediatric cancer patient population. As surgical treatment
can often prolong lives and even prevent premature deaths from these cancers, further
analysis of current surgical capacity can inform the path to meeting these critical
pediatric surgical needs.
Key-words:
Central nervous system cancers - Democratic People's Republic of Korea - neurosurgery
- pediatrics