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DOI: 10.4103/ajns.ajns_255_21
Intracranial myopericytoma: A rare benign tumor at an extremely rare location

A 50-year-old female with a history of seizures, headache, nausea, and vomiting. On imaging, parafalcine meningioma with mass effect features was rendered. She underwent right frontal tumor excision and craniotomy. Pathological examination showed a tumor composed of syncytial aggregates of round to plump fusiform cells forming whorls around prominent branching congested vessels. The tumorous cells expressed alpha-smooth muscle actin and heavy chain caldesmon and were negative for epithelial membrane antigen, protein S100, HMB45, CD34, calponin and desmin, thus providing the final diagnosis of intracranial myopericytoma. The rarity of this benign tumor at an extremely location, prompted this study. As preoperative radiological investigations are nonspecific in such cases, hence a detailed and comprehensive pathological examination is mandatory to come to a definitive diagnosis.
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Publication History
Received: 25 June 2021
Accepted: 03 August 2021
Article published online:
16 August 2022
© 2021. Asian Congress of Neurological Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
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References
- 1 Mentzel T. Myopericitoma, Including Myofibroma. WHO Classification of Soft Tissue and Bone Tumors. 4th ed. Lyon: IarC; 2013.
- 2 Rousseau A, Kujas M, van Effenterre R, Boch AL, Carpentier A, Leroy JP, et al. Primary intracranial myopericytoma: Report of three cases and review of the literature. Neuropathol Appl Neurobiol 2005;31:641-8.
- 3 Zhang CH, Hasegawa H, Johns P, Martin AJ. Myopericytoma of the posterior cranial fossa. Br J Neurosurg 2015;29:90-1.
- 4 Holling M, Wildförster U, Verheggen R, Müller K, Stummer W, Jeibmann A. Myopericytoma: A series of 5 cases affecting the nervous system. World Neurosurg 2015;84:8.e5-8.
- 5 Cox DP, Giltman L. Myopericytoma of the thoracic spine: A case report. Spine (Phila Pa 1976) 2003;28:E30-2.
- 6 Hunald FA, Rakotoarisoa JC, Razafimahatratra R, Andriamampionona F, Ravalisoa A, Randrianjafisamindrakotroka N. Thoracic myopericytoma in a child. A case report. Arch Pediatr 2008;15:1660-2.
- 7 Brunschweiler B, Guedj N, Lenoir T, Faillot T, Rillardon L, Guigui P. Oncogenous osteomalacia and myopericytoma of the thoracic spine: A case report. Spine (Phila Pa 1976) 2009;34:E857-60.
- 8 Chew LS, Han XJ, Tan KK, Bundele MM. Hemangiopericytoma of the thoracic spine: A case report. J Surg Case Rep 2017;2017:rjx121.
- 9 Agrawal N, Nag K. Myopericytoma of the thoracic spine: A case report and review of literature. Spine J 2013;13:e23-7.