Download PDF
CC BY-NC-ND 4.0 · Eur J Dent 2017; 11(04): 486-490
DOI: 10.4103/ejd.ejd_258_17
Original Article
Dental Investigation Society

The effect of two cross-linking agents on dentin bond strength of resin-modified glass ionomer

Fereshteh Shafiei
1   Oral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
,
Maryam Firouzmandi
1   Oral and Dental Disease Research Center, Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
,
Moona Zamanpour
2   Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran
› Author Affiliations
Further Information

Publication History

Publication Date:
01 October 2019 (online)

   Permissions and Reprints

ABSTRACT

Objectives: The hybrid layer at the interface of resin-modified glass ionomer cements and dentin is prone to degradation by endogenous matrix metalloproteinases. We aimed to investigate the effect of two types of collagen crosslinkers, carbodiimide and proanthocyanidin (PA), on immediate and medium-term bond strength of a resin-modified glass ionomer to dentin. Materials and Methods: Seventy-two molars were flattened on the occlusal surface to expose dentin. The specimens were divided into control, 1-ethyl-3-(3-dimethylaminopropy) carbodiimide hydrochloride (EDC), and PA groups (n = 24). In the EDC and PA groups, carbodiimide and PA solutions were applied for 1 min, respectively. Resin-modified glass ionomer was bonded. Half of the specimens in each group were tested for shear bond strength after 24 h and the other half were tested after 6 months. Statistical Analysis: Data were analyzed with SPSS version 16 (SPSS Inc, Chicago, IL, USA), using two-way ANOVA, and subgroup analysis was performed using one-way ANOVA, Tukey's test, and t-test. Results: Two-way ANOVA showed that treatment and time affected the bond strength. Carbodiimide and PA did not affect the immediate bond strength (P = 0.51). After 6 months, the bond strength of the EDC group was significantly lower than that of the control and PA groups. Bond strength of the control and PA groups increased after 6 months (P ≤ 0.002). Conclusion: PA did not interfere with maturation of RMGIC unlike carbodiimide. Therefore, it can be suggested as an matrix metalloproteinase inhibitor before bonding of resin-modified glass ionomer to dentin.

Key words:

Bond strength - carbodiimide - matrix metalloproteinase - proanthocyanidin - resin-modified glass ionomer
 

  • REFERENCES

  • 1 Yoshida Y, Van Meerbeek B, Nakayama Y, Snauwaert J, Hellemans L, Lambrechts P. et al. Evidence of chemical bonding at biomaterial-hard tissue interfaces. J Dent Res 2000; 79: 709-14
    Google Scholar
  • 2 Inoue S, Abe Y, Yoshida Y, De Munck J, Sano H, Suzuki K. et al. Effect of conditioner on bond strength of glass-ionomer adhesive to dentin/enamel with and without smear layer interposition. Oper Dent 2004; 29: 685-92
    PubMedGoogle Scholar
  • 3 Yap AU, Tan AC, Goh AT, Goh DC, Chin KC. Effect of surface treatment and cement maturation on the bond strength of resin-modified glass ionomers to dentin. Oper Dent 2003; 28: 728-33
    PubMedGoogle Scholar
  • 4 El-Askary FS, Nassif MS. The effect of the pre-conditioning step on the shear bond strength of nano-filled resin-modified glass-ionomer to dentin. Eur J Dent 2011; 5: 150-6
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Dursun E, Le Goff S, Ruse DN, Attal JP. Effect of chlorhexidine application on the long-term shear bond strength to dentin of a resin-modified glass ionomer. Oper Dent 2013; 38: 275-81
    CrossrefPubMedGoogle Scholar
  • 6 Fagundes TC, Toledano M, Navarro MF, Osorio R. Resistance to degradation of resin-modified glass-ionomer cements dentine bonds. J Dent 2009; 37: 342-7
    CrossrefPubMedGoogle Scholar
  • 7 Hashimoto M, Ohno H, Sano H, Kaga M, Oguchi H. In vitro degradation of resin-dentin bonds analyzed by microtensile bond test, scanning and transmission electron microscopy. Biomaterials 2003; 24: 3795-803
    CrossrefPubMedGoogle Scholar
  • 8 Hiraishi N, Sono R, Sofiqul I, Yiu C, Nakamura H, Otsuki M. et al. In vitro evaluation of plant-derived agents to preserve dentin collagen. Dent Mater 2013; 29: 1048-54
    CrossrefPubMedGoogle Scholar
  • 9 Nishitani Y, Yoshiyama M, Wadgaonkar B, Breschi L, Mannello F, Mazzoni A. et al. Activation of gelatinolytic/collagenolytic activity in dentin by self-etching adhesives. Eur J Oral Sci 2006; 114: 160-6
    CrossrefPubMedGoogle Scholar
  • 10 Tay FR, Pashley DH, Loushine RJ, Weller RN, Monticelli F, Osorio R. et al. Self-etching adhesives increase collagenolytic activity in radicular dentin. J Endod 2006; 32: 862-8
    CrossrefPubMedGoogle Scholar
  • 11 Hass V, Luque-Martinez IV, Gutierrez MF, Moreira CG, Gotti VB, Feitosa VP. et al. Collagen cross-linkers on dentin bonding: Stability of the adhesive interfaces, degree of conversion of the adhesive, cytotoxicity and in situ MMP inhibition. Dent Mater 2016; 32: 732-41
    CrossrefPubMedGoogle Scholar
  • 12 Mazzoni A, Apolonio FM, Saboia VP, Santi S, Angeloni V, Checchi V. et al. Carbodiimide inactivation of MMPs and effect on dentin bonding. J Dent Res 2014; 93: 263-8
    Google Scholar
  • 13 Bedran-Russo AK, Vidal CM, Dos Santos PH, Castellan CS. Long-term effect of carbodiimide on dentin matrix and resin-dentin bonds. J Biomed Mater Res B Appl Biomater 2010; 94: 250-5
    CrossrefPubMedGoogle Scholar
  • 14 Mazzoni A, Angeloni V, Apolonio FM, Scotti N, Tjäderhane L, Tezvergil-Mutluay A. et al. Effect of carbodiimide (EDC) on the bond stability of etch-and-rinse adhesive systems. Dent Mater 2013; 29: 1040-7
    CrossrefPubMedGoogle Scholar
  • 15 Al-Ammar A, Drummond JL, Bedran-Russo AK. The use of collagen cross-linking agents to enhance dentin bond strength. J Biomed Mater Res B Appl Biomater 2009; 91: 419-24
    Google Scholar
  • 16 Shafiei F, Yousefipour B, Mohammadi-Bassir M. Effect of carbodiimide on bonding durability of adhesive-cemented fiber posts in root canals. Oper Dent 2016; 41: 432-40
    CrossrefPubMedGoogle Scholar
  • 17 Scheffel DL, Hebling J, Scheffel RH, Agee K, Turco G, de Souza Costa CA. et al. Inactivation of matrix-bound matrix metalloproteinases by cross-linking agents in acid-etched dentin. Oper Dent 2014; 39: 152-8
    CrossrefPubMedGoogle Scholar
  • 18 Srinivasulu S, Vidhya S, Sujatha M, Mahalaxmi S. Shear bond strength of composite to deep dentin after treatment with two different collagen cross-linking agents at varying time intervals. Oper Dent 2012; 37: 485-91
    CrossrefPubMedGoogle Scholar
  • 19 Altunsoy M, Botsali MS, Korkut E, Kucukyilmaz E, Sener Y. Effect of different surface treatments on the shear and microtensile bond strength of resin-modified glass ionomer cement to dentin. Acta Odontol Scand 2014; 72: 874-9
    CrossrefPubMedGoogle Scholar
  • 20 Doozandeh M, Firouzmandi M, Mirmohammadi M. The simultaneous effect of extended etching time and casein phosphopeptide-amorphous calcium phosphate containing paste application on shear bond strength of etch-and-rinse adhesive to caries-affected dentin. J Contemp Dent Pract 2015; 16: 794-9
    CrossrefPubMedGoogle Scholar
  • 21 Shafiei F, Memarpour M. Effect of repeated use on dentin bond strength of two adhesive systems: All-in-one and one-bottle. Indian J Dent Res 2009; 20: 180-4
    CrossrefPubMedGoogle Scholar
  • 22 Han B, Jaurequi J, Tang BW, Nimni ME. Proanthocyanidin: A natural crosslinking reagent for stabilizing collagen matrices. J Biomed Mater Res A 2003; 65: 118-24
    PubMedGoogle Scholar
  • 23 Tezvergil-Mutluay A, Mutluay MM, Agee KA, Seseogullari-Dirihan R, Hoshika T, Cadenaro M. et al. Carbodiimide cross-linking inactivates soluble and matrix-bound MMPs, in vitro . J Dent Res 2012; 91: 192-6
    Google Scholar
  • 24 Beriat NC, Nalbant D. Water absorption and HEMA release of resin-modified glass-ionomers. Eur J Dent 2009; 3: 267-72
    Article in Thieme ConnectPubMedGoogle Scholar
  • 25 Cardoso MV, Delmé KI, Mine A, Neves Ade A, Coutinho E, De Moor RJ. et al. Towards a better understanding of the adhesion mechanism of resin-modified glass-ionomers by bonding to differently prepared dentin. J Dent 2010; 38: 921-9
    CrossrefPubMedGoogle Scholar
  • 26 Wan AC, Yap AU, Hastings GW. Acid-base complex reactions in resin-modified and conventional glass ionomer cements. J Biomed Mater Res 1999; 48: 700-4
    CrossrefPubMedGoogle Scholar
  • 27 Mount GJ. Glass ionomers: A review of their current status.. Oper Dent 1999; 24: 115-24
    PubMedGoogle Scholar
  • 28 Hashimoto M, Ohno H, Sano H, Tay FR, Kaga M, Kudou Y. et al. Micromorphological changes in resin-dentin bonds after 1 year of water storage. J Biomed Mater Res 2002; 63: 306-11
    CrossrefPubMedGoogle Scholar