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CC BY-NC-ND 4.0 · Ibnosina Journal of Medicine and Biomedical Sciences 2019; 11(03): 128-130
DOI: 10.4103/ijmbs.ijmbs_35_19
Case Report

En bloc kidney transplant from pediatric donor to an adult

Navdeep Singh
1   Division of Transplantation Surgery, Wexner Medical Center, Ohio State University, Columbus, Ohio, USA
,
Elmahdi Elkhammas
1   Division of Transplantation Surgery, Wexner Medical Center, Ohio State University, Columbus, Ohio, USA
,
Amer Rajab
1   Division of Transplantation Surgery, Wexner Medical Center, Ohio State University, Columbus, Ohio, USA
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The use of pediatric kidney donors is not a common practice. Transplant physicians and surgeons are concerned with technical issues as well as inadequate nephrons mass. We reported a case of en bloc kidney transplant from a pediatric donor to serve as a teaching case. The donor is a 3-year-old infant who died as a result of influenza. Due to the age and size discrepancy with an adult, it was decided to transplant the kidneys en bloc into an adult with successful outcome. En bloc technique renders the kidneys transplantable which would have been otherwise discarded and theoretically protect against hyperfiltration injury. Small pediatric donors are excellent resources and should be considered for donation whenever option is available.

Key-words:

En bloc kidney transplant - end-stage renal disease - glomerular filtration rate - inferior vena cava - kidney transplantation - single kidney transplant - standard criteria donor transplant

Financial support and sponsorship

Nil.




Publication History

Received: 01 July 2019

Accepted: 03 September 2019

Article published online:
07 July 2022

© 2019. The Libyan Authority of Scientific Research and Technologyand the Libyan Biotechnology Research Center. All rights reserved. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License,permitting copying and reproductionso long as the original work is given appropriate credit. Contents may not be used for commercial purposes, oradapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Tonelli M, Wiebe N, Knoll G, Bello A, Browne S, Jadhav D, et al. Systematic review: Kidney transplantation compared with dialysis in clinically relevant outcomes. Am J Transplant 2011;11:2093-109.
  • 2 Sánchez-Fructuoso AI, Prats D, Pérez-Contín MJ, Marques M, Torrente J, Conesa J, et al. Increasing the donor pool using en bloc pediatric kidneys for transplant. Transplantation 2003;76:1180-4.
  • 3 Dharnidharka VR, Stevens G, Howard RJ. En-bloc kidney transplantation in the United States: An analysis of United Network of Organ Sharing (UNOS) data from 1987 to 2003. Am J Transplant 2005;5:1513-7.
  • 4 Organ Procurement and Transplantation Network Data; 2018. Available from: https://optn.transplant.hrsa.gov/data/view-data-reports/. [Last accessed on 2019 Jan 18].
  • 5 Brenner BM, Cohen RA, Milford EL. In renal transplantation, one size may not fit all. J Am Soc Nephrol 1992;3:162-9.
  • 6 Sureshkumar KK, Reddy CS, Nghiem DD, Sandroni SE, Carpenter BJ. Superiority of pediatric en bloc renal allografts over living donor kidneys: A long-term functional study. Transplantation 2006;82:348-53.
  • 7 Marques M, Prats D, Sánchez-Fuctuoso A, Naranjo P, Herrero JA, Contreras E, et al. Incidence of renal artery stenosis in pediatric en bloc and adult single kidney transplants. Transplantation 2001;71:164-6.
  • 8 Bresnahan BA, McBride MA, Cherikh WS, Hariharan S. Risk factors for renal allograft survival from pediatric cadaver donors: An analysis of united network for organ sharing data. Transplantation 2001;72:256-61.
  • 9 Hayes JM, Steinmuller DR, Streem SB, Novick AC. The development of proteinuria and focal-segmental glomerulo-sclerosis in recipients of pediatric donor kidneys. Transplantation 1991;52:813-7.
  • 10 Neumayer HH, Huls S, Schreiber M, Riess R, Luft FC. Kidneys from pediatric donors: Risk versus benefit. Clin Nephrol 1994;41:94-100.
  • 11 Hayes JM, Novick AC, Streem SB, Hodge EE, Bretan PN, Graneto D, et al. The use of single pediatric cadaver kidneys for transplantation. Transplantation 1988;45:106-10.
  • 12 Mohanka R, Basu A, Shapiro R, Kayler LK. Single versus en bloc kidney transplantation from pediatric donors less than or equal to 15 kg. Transplantation 2008;86:264-8.
  • 13 Gruessner RW, Matas AJ, Lloveras G, Fryd DS, Dunn DL, Payne WD, et al. A comparison of single and double pediatric cadaver donor kidneys for transplantation. Clin Transplant 1989;3:209-14.
  • 14 Bhayana S, Kuo YF, Madan P, Mandaym S, Thomas PG, Lappin JA, et al. Pediatric en bloc kidney transplantation to adult recipients: More than suboptimal? Transplantation 2010;90:248-54.