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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(02): 226-227
DOI: 10.4103/ijmpo.ijmpo_150_16
Case Report

Bulky Pelvic Hodgkin Lymphoma in a Prepubertal Girl

Sidharth Totadri
Department of Pediatrics, Advanced Pediatrics Center, Pediatric Hematology-Oncology Unit, Chandigarh, India
,
Deepak Bansal
Department of Pediatrics, Advanced Pediatrics Center, Pediatric Hematology-Oncology Unit, Chandigarh, India
,
Amanjit Bal
Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Prema Menon
Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Pure infra-diaphragmatic presentation is rare in pediatric Hodgkin lymphoma (HL). Isolated pelvic presentation is restricted to case reports in adults. We describe a unique presentation of HL as a primary pelvic disease in an 11-year-old prepubertal girl. She was treated based on the Euronet-Paediatric Hodgkin's Lymphoma Group protocol (EuroNet-PHL-C1) recommendations and assigned to treatment Group 2 (Stage IIB). The patient had bulky disease and a suboptimal response on interim 18-fluorodeoxyglucose positron emission tomography. The child was administered chemotherapy alone. Pelvic radiotherapy was consciously avoided due to the high risk of gonadal failure. She remains disease-free for 18 months now. Treatment of pediatric HL necessitates a delicate balance between achieving cure as well as avoiding serious late effects of therapy.

Keywords

Hypogonadism - infradiaphragmatic - late effects - positron emission tomography scan - radiation


Publication History

Article published online:
06 July 2021

© 2017. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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