A Novel Translocation: t(2;14)(p12;q32) in a Case of Precursor B‑acute Lymphoblastic Leukemia

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2017; 38(03): 407-408
DOI: 10.4103/ijmpo.ijmpo_172_16

Letters to Editor

Prasannakumari Sampathkumar

Department of Pathology, Cytogenetics Unit, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka

,

Shanthi Velusamy

Department of Pathology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka

,

Namrata Rajkumar

Department of Pathology, Hematology Unit, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka

,

M Padma

Department of Paediatric Oncology, Kidwai Memorial Institute of Oncology, Bengaluru, Karnataka

References
1 Woo JS, Alberti MO, Tirado CA. Childhood B-acute lymphoblastic leukemia: A genetic update. Exp Hematol Oncol 2014;3:16.
2 Dyer MJ, Akasaka T, Capasso M, Dusanjh P, Lee YF, Karran EL, et al. Immunoglobulin heavy chain locus chromosomal translocations in B-cell precursor acute lymphoblastic leukemia: Rare clinical curios or potent genetic drivers? Blood 2010;115:1490-9.
3 Huh J, Mun YC, Yoo ES, Seong CM, Chung WS. Submicroscopic deletions of immunoglobulin heavy chain gene (IGH) in precursor B lymphoblastic leukemia with IGH rearrangements. Ann Lab Med 2015;35:128-31.
4 Shaffer LG, McGowan-Jordan J, Schmid M. ISCN 2013: An International System for Human Cytogenetic Nomenclature. Basel: Karger Publishers; 2013.
5 Inaba T, Oku N, Gotoh H, Murakami S, Oku N, Itoh K, et al. Philadelphia chromosome positive precursor B-cell acute lymphoblastic leukemia with a translocation t(2;14)(p13;q32). Leukemia 1991;5:719-22.
6 Kerketta L, Vundinti BR, Ghosh K. Translocation t(2;14)(p13;q32) in a case of Ph+ acute lymphoblastic leukemia. Indian J Hum Genet 2007;13:125-6.
7 Watson MS, Land VJ, Carroll AJ, Pullen J, Borowitz MJ, Link MP, et al. t(2;14)(p13;q32): A recurring abnormality in lymphocytic leukemia. A Pediatric Oncology Group study. Cancer Genet Cytogenet 1992;58:121-4.
8 Berkowicz M, Toren A, Rosner E, Biniaminov M, Rosenthal E, Gipsh N, et al. Translocation (2;14)(p13;q32) in CD10+; CD13+ acute lymphatic leukemia. Cancer Genet Cytogenet 1995;83:140-3.Sir,