CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2019; 40(S 01): S157-S159
DOI: 10.4103/ijmpo.ijmpo_229_17
Case Report

Large Plaque Parapsoriasis in a Child: A Rare Entity in Pediatric Oncology

Bahareh Abtahi-Naeini
Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan
,
Farahnaz Fatemi Naeini
Department of Dermatology, Isfahan University of Medical Sciences, Isfahan
,
Mohammad Faranoush
Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences, Tehran
,
Najmeh Bolandnazar
Department of Dermatology Arak University of Medical Sciences, Arak, Iran
› Author Affiliations
Financial support and sponsorship This study is financially supported by Isfahan University of Medical Sciences, Isfahan, Iran.

Abstract

Parapsoriasis is exceedingly rare in children. The presentation, course, and prognosis of parapsoriasis in children have not yet been completely elucidated. Here, a case of large plaque parapsoriasis in 10-year-old boy is reported who was diagnosed recalcitrant pediatrics eczema for about 5 years. Other clinicians had previously treated him with emollients and topical corticosteroids with temporary relief but without improvement. The erythematous scaly patches were situated on the trunk and flank. On skin biopsy, the lymphocytic infiltrate was composed mainly of CD4+ and CD45RO+ lymphocytes. No T-cell receptor gene rearrangements were found. The paucity of knowledge about the evolution of this entity in childhood and its relationship to mycosis fungoides makes follow-up critical.



Publication History

Article published online:
24 May 2021

© 2019. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Salava A, Pereira P, Aho V, Väkevä L, Paulin L, Auvinen P. et al. Skin microbiome in small- and large-plaque parapsoriasis. Acta Derm Venereol 2017; 97: 685-91
  • 2 Simon M, Flaig MJ, Kind P, Sander CA, Kaudewitz P. Large plaque parapsoriasis: Clinical and genotypic correlations. J Cutan Pathol 2000; 27: 57-60
  • 3 Nag F, Ghosh A, Biswas P, Chatterjee G, Biswas S. Ichthyosiform large plaque parapsoriasis: Report of a rare entity. Indian J Dermatol 2013; 58: 385-7
  • 4 Fatemi Naeini F, Sadeghiyan H, Pourazizi M, Najafian J, Abtahi-Naeini B. Characteristics of primary cutaneous T-cell lymphoma in Iran: A 10-year retrospective study. Int Sch Res Notices 2014; 2014: 820921
  • 5 Olsen E, Vonderheid E, Pimpinelli N, Willemze R, Kim Y, Knobler R. et al. Revisions to the staging and classification of mycosis fungoides and Sezary syndrome: A proposal of the International Society for Cutaneous Lymphomas (ISCL) and the cutaneous lymphoma task force of the European Organization of Research and Treatment of Cancer (EORTC). Blood 2007; 110: 1713-22
  • 6 Väkevä L, Sarna S, Vaalasti A, Pukkala E, Kariniemi AL, Ranki A. et al. A retrospective study of the probability of the evolution of parapsoriasis en plaques into mycosis fungoides. Acta Derm Venereol 2005; 85: 318-23
  • 7 Naeini FF, Abtahi-Naeini B, Pourazizi M, Sadeghiyan H, Najafian J. Primary cutaneous lymphomas: A clinical and histological study of 99 cases in Isfahan, Iran. J Res Med Sci 2015; 20: 827-31
  • 8 Haeffner AC, Smoller BR, Zepter K, Wood GS. Differentiation and clonality of lesional lymphocytes in small plaque parapsoriasis. Arch Dermatol 1995; 131: 321-4
  • 9 Fatemi Naeini F, Abtahi-Naeini B, Najafian J, Saffaei A, Pourazizi M. Correlation between mycosis fungoides and pregnancy. Saudi Med J 2016; 37: 968-72
  • 10 Lazar AP, Caro WA, Roenigk Jr. HH, Pinski KS. Parapsoriasis and mycosis fungoides: The Northwestern University experience, 1970 to 1985. J Am Acad Dermatol 1989; 21: 919-23
  • 11 Menni S, Piccinno R, Crosti L, Berti E. Parapsoriasis in two children: A clinical, immunophenotypic, and immunogenotypic study. Pediatr Dermatol 1994; 11: 151-5
  • 12 Das JK, Gangopadhyay AK. Large plaque parapsoriasis in a child. Indian J Dermatol 2005; 50: 221-3
  • 13 Zackheim HS, Kashani-Sabet M, Amin S. Topical corticosteroids for mycosis fungoides. Experience in 79 patients. Arch Dermatol 1998; 134: 949-54
  • 14 Zackheim HS. Treatment of patch-stage mycosis fungoides with topical corticosteroids. Dermatol Ther 2003; 16: 283-7