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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(01): 4-7
DOI: 10.4103/ijmpo.ijmpo_239_14
Original Article

An Epidemiological Review of Sacrococcygeal Teratoma over Five Years in a Tertiary Care Hospital

Mukhopadhyay Bedabrata
Department of Biochemistry, Banaras Hindu University, Varanasi, Uttar Pradesh, India
,
Das Chhanda
Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
,
Sengupta Moumita
Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
,
Saha Ashis Kumar
Department of Surgery, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
,
Mukhopadhyay Madhumita
Department of Pathology, Institute of Post Graduate Medical Education and Research, Kolkata, West Bengal, India
,
Mukhopadhyay Biswanath
Department of Pediatric Surgery, Nil Ratan Sircar Medical College and Hospital, Kolkata, West Bengal, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Background: Teratoma refers to neoplasm containing at least two germ cell layers derivatives foreign to the site of origin. Sacrococcygeal teratoma is most common congenital tumor commonly present as an exophytic mass of varying size at coccyx. Aims and Objectives: (1) The aim is to find age, sex, and clinical presentation of cases of sacrococcygeal teratoma. (2) Application of American Academy of Pediatrics' surgical section classification and histological grading in all cases. Materials and Methods: A retrospective, observational study was conducted in the Department of Pathology in collaboration with the Department of Pediatric Surgery from February 2009 to January 2014. A total 13 cases of sacrococcygeal teratoma were included in the present study. The records of these patients were reviewed, and clinical profiles were noted. An average 12 slides were examined in each case to evaluate histological type and grades. Results: A retrospective study was conducted including thirteen cases of histologically confirmed sacrococcygeal teratoma over 5 years period. Male to female ratio was 1:2. As per as age distribution is concerned, 3 neonates (23%) presented with sacrococcygeal mass. Associated congenital malformation was seen in 2 cases (15.4%). According to the American Academy of Pediatrics (Altman's) classification, 23% of cases were Type I, 31% of cases patients Type II, 31% of cases Type III and 15% were for Type IV. The significant presacral component was noted in all malignant tumors. Conclusion: Two clinical patterns were observed in sacrococcygeal teratoma related to the age of presentation. As sacrococcygeal teratoma has potential to become malignant, meticulous search for the malignant component is required for histopathological categorization.

Keywords

Neuroepithelium - sacrococcygeal teratoma - Totipotential cell


Publication History

Article published online:
23 June 2021

© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)

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