An Unusual Tumor of the Vagina

Archana Archana; Saritha Shamsunder; Amit Yadav; Sunita Malik

doi:10.4103/ijmpo.ijmpo_239_17

Indian Journal of Medical and Paediatric Oncology, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2019; 40(S 01): S123-S125
DOI: 10.4103/ijmpo.ijmpo_239_17

Case Report

An Unusual Tumor of the Vagina

Authors

Archana Archana

Departments of Gynaecology, Vardhmaan Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
Saritha Shamsunder

Departments of Gynaecology, Vardhmaan Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
Amit Yadav

Departments of Pathology, Vardhmaan Mahaveer Medical College and Safdarjung Hospital, New Delhi, India
Sunita Malik

Departments of Gynaecology, Vardhmaan Mahaveer Medical College and Safdarjung Hospital, New Delhi, India

Abstract

A 28-year-old female came with complaints of swelling in the perineal area; examination revealed a nontender and fixed mass of approximately 4 cm × 3 cm on the right vulvovaginal junction extending into the vaginal wall. Wide excision of the mass was performed; histopathological examination revealed features suggestive of Merkel cell carcinoma of vagina.

Keywords

Cytokeratin - Merkel cell carcinoma - vulvovaginal mass

Volltext

Referenzen

References
1 Koljonen V. Merkel cell carcinoma. World J Surg Oncol 2006; 4: 7
2 Barrett AW, Cort EM, Patel P, Berkovitz BK. An immunohistological study of cytokeratin 20 in human and mammalian oral epithelium. Arch Oral Biol 2000; 45: 879-87
3 Hilliges M, Falconer C, Ekman-Ordeberg G, Johansson O. Innervation of the human vaginal mucosa as revealed by PGP 9.5 immunohistochemistry. Cells Tissues Organs 1995; 153: 119-26
4 Skelton HG, Smith KJ, Hitchcock CL, McCarthy WF, Lupton GP, Graham JH. et al. Merkel cell carcinoma: Analysis of clinical, histologic, and immunohistologic features of 132 cases with relation to survival. J Am Acad Dermatol 1997; 37: 734-9
5 Moll R, Löwe A, Laufer J, Franke WW. Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol 1992; 140: 427-47
6 Chan JK, Suster S, Wenig BM, Tsang WY, Chan JB, Lau AL. et al. Cytokeratin 20 immunoreactivity distinguishes merkel cell (primary cutaneous neuroendocrine) carcinomas and salivary gland small cell carcinomas from small cell carcinomas of various sites. Am J Surg Pathol 1997; 21: 226-34
7 Devoe K, Weidner N. Immunohistochemistry of small round-cell tumors. Semin Diagn Pathol 2000; 17: 216-24
8 Nagao T, Gaffey TA, Olsen KD, Serizawa H, Lewis JE. Small cell carcinoma of the major salivary glands: Clinicopathologic study with emphasis on cytokeratin 20 immunoreactivity and clinical outcome. Am J Surg Pathol 2004; 28: 762-70
9 Finan MA, Barre G. Bartholin’s gland carcinoma, malignant melanoma and other rare tumours of the vulva. Best Pract Res Clin Obstet Gynaecol 2003; 17: 609-33
10 Iavazzo C, Terzi M, Arapantoni-Dadioti P, Dertimas V, Vorgias G. Vulvar merkel carcinoma: A case report. Case Rep Med 2011; 2011: 546972