Secondary Juvenile Myelo-Monocytic Leukemia in a Patient with Congenital Amegakaryocytic Thrombocytopenia

References
1 King S, Germeshausen M, Strauss G, Welte K, Ballmaier M. Congenital amegakaryocytic thrombocytopenia: A retrospective clinical analysis of 20 patients. Br J Haematol 2005; 131: 636-44
2 Ballmaier M, Germeshausen M. Advances in the understanding of congenital amegakaryocytic thrombocytopenia. Br J Haematol 2009; 146: 3-16
3 Ballmaier M, Germeshausen M, Schulze H, Cherkaoui K, Lang S, Gaudig A. et al. c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia. Blood 2001; 97: 139-46
4 Ihara K, Ishii E, Eguchi M, Takada H, Suminoe A, Good RA. et al. Identification of mutations in the c-mpl gene in congenital amegakaryocytic thrombocytopenia. Proceed Natl Academy Sci United States Am 1999; 96: 3132-36
5 Ballmaier M, Germeshausen M, Schulze H, Cherkaoui K, Lang S. et al. c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia. Blood 2001; 97: 139-46
6 Zaninetti C, Gresele P, Bertomoro A. et al. Eltrombopag for the treatment of inherited thrombocytopenias: a phase 2 clinical trial. Haematologica 2020; 105: 820-8
7 Pecci A. Pathogenesis and management of inherited thrombocytopenias: Rationale for the use of thrombopoietin-receptor agonists. Int J Hematol 2013; 98: 34-47
8 Maserati E, Panarello C, Morerio C, Valli R, Pressato B, Patitucci F. et al. Clonal chromosome anomalies and propensity to myeloid malignancies in congenital amegakaryocytic thrombocytopenia (OMIM 604498). Haematologica 2008; 93: 1271-3
9 Alter BP. Inherited bone marrow failure syndromes. In: Nathan DG, Stranahan RA, Orkin SH, Look AT, Ginsburg D. editors Nathan and Oski's Hematology of Infancy and Childhood. Philadelphia: Saunders W.B; 2003: 280-365