Subscribe to RSS
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.4103/ijmpo.ijmpo_385_20
Diffuse Anterior Retinoblastoma Masquerading as Complicated Cataract - A Case Report
Financial support and sponsorship Nil.![](https://www.thieme-connect.de/media/10.1055-s-00050348/202006/lookinside/thumbnails/10_4103_ijmpo_ijmpo_385_20_923-1.jpg)
Abstract
Diffuse anterior retinoblastoma (Rb) is a rare variant of this tumor which may involve the anterior chamber of the eye without any detectable mass in the posterior segment. The initial presentation of this tumor as anterior segment pathology may lead to misdiagnosis and erroneous management eventually delaying the definitive therapy. We describe an 8-year-old child presenting with complicated cataract who underwent lens aspiration and later found to have diffuse anterior Rb.
Publication History
Received: 10 August 2020
Accepted: 02 October 2020
Article published online:
14 May 2021
© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/.)
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Hurwitz RL, Shields CL, Shields JA, Barrios PC, Gombos DS, Hurwitz MY. et al. Retinoblastoma. In: Pizzo PA, Poplack DG. editors Principles and Practice of Pediatric Oncology. Philadelphia: Wolters Kluwer Health; 2016. 7. 700-25
- 2 Jijelava KP, Grossniklaus HE. et al. Diffuse anterior retinoblastoma: A review. Saudi J Ophthalmol 2013; 27: 135-9
- 3 Sinha S, Grossniklaus HE, Dhaliwal RS, Martin DF. Diffuse anterior retinoblastoma. Retina 1998; 18: 238-41
- 4 Balasubramanya R, Pushker N, Bajaj MS, Ghose S, Kashyap S, Rani A. et al. Atypical presentations of retinoblastoma. J Pediatr Ophthalmol Strabismus 2004; 41: 18-24
- 5 Shields CL, Ghassemi F, Tuncer S, Thangappan A, Shields JA. Clinical spectrum of diffuse infiltrating retinoblastoma in 34 consecutive eyes. Ophthalmology 2008; 115: 2253-8
- 6 Crosby MB, Hubbard GB, Gallie BL, Grossniklaus HE. Anterior diffuse retinoblastoma: Mutational analysis and immunofluorescence staining. Arch Pathol Lab Med 2009; 133: 1215-8
- 7 Garner A, Kanski JJ, Kinnear F. Retinoblastoma: Report of a case with minimal retinal involvement but massive anterior segment spread. Br J Ophthalmol 1987; 71: 858-63
- 8 Khetan V, Sudrik S, Singh S, Gopal L, Krishnakumar S. Diffuse anterior retinoblastoma with undetectable retinal involvement. J Pediatr Ophthalmol Strabismus 2011; 48 Online: e7-9
- 9 Shields CL, Lally SE, Manjandavida FP, Leahey AM, Shields JA. Diffuse anterior retinoblastoma with globe salvage and visual preservation in 3 consecutive cases. Ophthalmology 2016; 123: 378-84
- 10 Kitazawa K, Nagata K, Yamanaka Y, Iehara T, Kinoshita S. et al. Diffuse anterior retinoblastoma with sarcoidosis-like nodule. Case Rep Ophthalmol 2015; 6: 443-7
- 11 Kelly A, Kaufman SC, Ali R, Grajewski A, Anderson J. Rare anterior segment retinoblastoma masquerading as corneal endotheliitis. Eye Contact Lens 2016; 42: e1-3
- 12 Georgalas I, Koutsandrea C, Paraskevopoulos T, Petrou P, Sarin YK. White balls in the anterior chamber: A potentially life-threatening condition. NeoJ Pediatrnat 2016; 170: 337-e1
- 13 Rao R, Honavar SG, Mulay K, Reddy VAP. Eye salvage in diffuse anterior retinoblastoma using systemic chemotherapy with periocular and intravitreal topotecan. J AAPOS 2018; 22: 235-700
- 14 Herwig MC, Hubbard GB, Wells JR, Grossniklaus HE. Diffuse anterior retinoblastoma. Ophthalmologe 2011; 108: 969-72
- 15 Longmuir SQ, Syed NA, Boldt HC. Diffuse anterior retinoblastoma without retinal involvement. Ophthalmology 2010; 117: 2034-8