CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2019; 40(04): 579-580
DOI: 10.4103/ijmpo.ijmpo_77_18
Case Report

Secondary Osteosarcoma of Pelvic Bone: Long-Term Complication of Bladder Cancer Radiotherapy

K Siva Prasad
Department of Medical Oncology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India
,
Stalin Bala
Department of Medical Oncology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India
,
Ambalathandi Ravichandran
Department of Medical Oncology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India
,
Gundeti Sadashivudu
Department of Medical Oncology, Nizam’s Institute of Medical Sciences, Hyderabad, Telangana, India
› Author Affiliations
Financial support and sponsorship Nil.

Abstract

Second cancer in the irradiated area is one of the complication of radiotherapy of which bone and soft tissue sarcomas predominate. Radiation-induced osteosarcoma (RIOS)accounts for 3.4%–5.5% of all osteosarcoma cases. A 70-year old male presented with complaints of swelling and pain in left gluteal region without any antecedent trauma. On clinical examination 8 × 8 cm size swelling palpable in left gluteal region arising form left iliac bone. He had history of bladder carcinoma 20 years ago for which he received concurrent chemoradiation. CT scan showed a large, erosive and lytic lesion of left iliac bone and biopsy of the lesion was suggestive of osteosarcoma. In view of extensive lesion eroding left half of pelvic bone, surgery was not done, and chemotherapy was planned.



Publication History

Received: 06 April 2018

Accepted: 21 June 2018

Article published online:
03 June 2021

© 2020. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Ferrie BG, Imrie JE, Paterson PJ. Osteosarcoma of bladder 27 years after local radiotherapy. J R Soc Med 1984; 77: 962-3
  • 2 Mohan H, Ahal S, Nada R, Jogai S, Attri AK. Osteosarcoma of the bladder – A case report. Indian J Pathol Microbiol 2001; 44: 451-2
  • 3 Brady MS, Gaynor JJ, Brennan MF. Radiation-associated sarcoma of bone and soft tissue. Arch Surg 1992; 127: 1379-85
  • 4 Huvos AG, Woodard HQ, Cahan WG, Higinbotham NL, Stewart FW, Butler A. et al. Postradiation osteogenic sarcoma of bone and soft tissues. A clinicopathologic study of 66 patients. Cancer 1985; 55: 1244-55