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CC BY-NC-ND 4.0 · Indian J Med Paediatr Oncol 2018; 39(04): 452-455
DOI: 10.4103/ijmpo.ijmpo_90_17
Original Article

Opportunistic Screening for Detection and Socio-epidemiological Risk Assessment of Oral Cancer Patients in Rural Jodhpur, India

Jitendra Kumar Meena
Department of Community Medicine, Geetanjali Medical College and Hospital, Udaipur
,
Anjana Verma
Department of Community Medicine, Geetanjali Medical College and Hospital, Udaipur
,
Sandeep Kumar Upadhyay
Department of Community and Family Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India
› Institutsangaben Financial support and sponsorship Nil.
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Abstract

Background: Globally, India has a high burden (20%) of oral cancer with 1% prevalence of premalignant lesions. Most cases are attributed to modifiable risk factors such as substance abuse (tobacco and alcohol), dietary deficiencies, and environmental exposures (solar radiation and air pollution) aggravated by delayed detection and care especially in rural areas. Objective: The objective of the study was to study the risk factors of oral cancer pathogenesis among the rural residents of Jodhpur, India, through opportunistic oral screening approach at primary care facilities. Methodology: An unmatched case–control study was done at two randomly chosen rural health centres in Jodhpur, India. A total of 84 cases and 168 controls were included during 6 months study period (2016). Randomly selected outpatient department attendees were interviewed and screened for oral cancer and premalignant lesions. A structured questionnaire interview along with comprehensive oral, head and neck examination was conducted. Data were analyzed using multivariate logistic regression, and confidentiality of data was maintained. Results: The majority of the study participants were rural residents (82.9%) with poor socioeconomic status. Opportunistic oral screening revealed a variety of cancerous and precancerous lesions. Most common case pathologies were submucosal fibrosis (40.5%), inadequate mouth opening (35.7%), cheek bites (28.6%), leukoplakia (23.8%) etc. Multivariate analysis suggested that tobacco intake (adjusted odds ratio = 13.6, P ≤ 0.01) dietary deficiency (7.4, <0.01), oral sepsis (7.0, <0.01), oral lesions (6.8, <0.01), and sun radiation exposure (9.5, <0.01) were significantly associated with oral cancer pathology. Conclusion: The study provides strong evidence that tobacco, dietary deficiency, oral sepsis and lesions, and sun radiation exposure are independent risk factors for oral cancer. It also reiterates the importance and application of opportunistic oral cancer screening at primary care level.

Keywords

Case control - India - NPCDCS - Opportunistic screening - Oral cancer - Oral pathology - Tobacco


Publikationsverlauf

Artikel online veröffentlicht:
17. Juni 2021

© 2018. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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  • References

  • 1 Nair DR, Pruthy R, Pawar U, Chaturvedi P. Oral cancer: Premalignant conditions and screening – An update. J Cancer Res Ther 2012; 8 (01) Suppl S57-66
    CrossrefPubMedGoogle Scholar
  • 2 Blot WJ. Alcohol and cancer. Cancer Res 1992; 52: 2119s-23s
    PubMedGoogle Scholar
  • 3 British Dental Association. Opportunistic Oral Cancer Screening. BDA Occasional Paper; April, 2000.
  • 4 Babu S, Bhat RV, Kumar PU, Sesikaran B, Rao KV, Aruna P. et al. A comparative clinico-pathological study of oral submucous fibrosis in habitual chewers of pan masala and betel quid. J Toxicol Clin Toxicol 1996; 34: 317-22
    CrossrefPubMedGoogle Scholar
  • 5 International Institute for Population Sciences. India National Family Health Survey (NFHS-4), 2015-16. International Institute for Population Sciences; 2017
    Google Scholar
  • 6 Johnson NW, Warnakulasuriya KA, Partridge M, Langdon JD. Oral cancer: A serious and growing problem. Ann R Coll Surg Engl 1995; 77: 321-2
    PubMedGoogle Scholar
  • 7 Blot WJ, McLaughlin JK, Winn DM, Austin DF, Greenberg RS, Preston-Martin S. et al. Smoking and drinking in relation to oral and pharyngeal cancer. Cancer Res 1988; 48: 3282-7
    PubMedGoogle Scholar
  • 8 National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke (NPCDCS). Available from: http://www.health.bih.nic.in/Docs/Guidelines/Guidelines-NPCDCS.pdf. [Last accessed on 2015 Dec 19].
  • 9 Singh MP, Misra S, Rathanaswamy SP, Gupta S, Tewari BN, Bhatt ML. et al. Clinical profile and epidemiological factors of oral cancer patients from North India. Natl J Maxillofac Surg 2015; 6: 21-4
    CrossrefPubMedGoogle Scholar
  • 10 Madani AH, Dikshit M, Bhaduri D. Risk for oral cancer associated to smoking, smokeless and oral dip products. Indian J Public Health 2012; 56: 57-60
    CrossrefPubMedGoogle Scholar
  • 11 Mahapatra S, Kamath R, Shetty BK, Binu VS. Risk of oral cancer associated with gutka and other tobacco products: A hospital-based case-control study. J Cancer Res Ther 2015; 11: 199-203
    CrossrefPubMedGoogle Scholar
  • 12 Schildt EB, Eriksson M, Hardell L, Magnuson A. Oral snuff, smoking habits and alcohol consumption in relation to oral cancer in a Swedish case-control study. Int J Cancer 1998; 77: 341-6
    CrossrefPubMedGoogle Scholar
  • 13 Villa A, Kreimer AR, Pasi M, Polimeni A, Cicciù D, Strohmenger L. et al. Oral cancer knowledge: A survey administered to patients in dental departments at large Italian hospitals. J Cancer Educ 2011; 26: 505-9
    CrossrefPubMedGoogle Scholar
  • 14 Nunn H, Lalli A, Fortune F, Croucher R. Oral cancer screening in the Bangladeshi community of Tower Hamlets: A social model. Br J Cancer 2009; 101 (02) Suppl S68-72
    CrossrefPubMedGoogle Scholar