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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2020; 30(03): 400-404
DOI: 10.4103/ijri.IJRI_125_20
Case Report

111In-Octreoscan SPECT/CT hybrid imaging and 68Ga-DOTANOC PET/CT in neuroendocrine adenoma of the middle ear (NAME)

Mariano Pontico
Department of Medico-Surgical Sciences and Biotechnologies, Ph.D. Program in Morphogenesis and Tissue Engineering
,
Viviana Frantellizzi
Department of Medico-Surgical Sciences and Biotechnologies, Ph.D. Program in Morphogenesis and Tissue Engineering
,
Laura Cosma
Departments of Molecular Medicine, Sapienza University of Rome, Viale Regina Elena 324, Rome, Italy
,
Giuseppe De Vincentis
Departments of Radiological Sciences, Oncology and Anatomical Pathology, Sapienza University of Rome, Viale Regina Elena 324, Rome, Italy
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Neuroendocrine adenoma of the middle ear (NAME) represents a rare tumour consisting of an adenoma with mixed neuroendocrine differentiation. A 40-year-old woman was referred to our attention to further investigate the occurrence of a pathological tissue located in the mastoid process of the left temporal bone depicted by head CT and MRI scans. Histopathological examination revealed an epithelial neoplasm with neuroendocrine differentiation features, consistent with the diagnosis of NAME. In order to obtain an accurate differential diagnosis and confirmation of this rare disease, 111In-Octreoscan single photon emission computed tomography (SPECT)/CT and 68Ga-DOTANOC positron emission tomography (PET)/CT were performed, both showing overexpression of somatostatin receptors and thus corroborating the histopathological findings.

Keywords

111In-Octreoscan SPECT - 68Ga-DOTANOC PET/CT - carcinoid - hybrid SPECT/CT imaging - middle ear adenoma - NAME - NET


Publication History

Received: 19 March 2020

Accepted: 05 June 2020

Article published online:
19 July 2021

© 2020. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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