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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2019; 29(02): 133-140
DOI: 10.4103/ijri.IJRI_354_18
Gastro-Intestinal Imaging

Gastrointestinal Stromal Tumor (GIST) from esophagus to anorectum – diagnosis, response evaluation and surveillance on computed tomography (CT) scan

Sushil N Panbude
Departments of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India
,
Suman K Ankathi
Departments of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India
,
Anant T Ramaswamy
Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India
,
Avanish P Saklani
Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India
› Author Affiliations
Subject Editor: Financial support and sponsorship Nil.
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Abstract

Gastrointestinal stromal tumor (GIST) are the most common non epithelial tumor of the gastrointestinal (GI) tract. They arise from interstitial cells of Cajal present in the myenteric plexus. They can also arise outside the GI tract from mesentery, retro peritoneum and omentum. With the advent of new targeted molecular therapy c- tyrosine kinase inhibitor (Imatinib), it has become important to differentiate between response and pseudo-progression of the disease as response evaluation criteria for GIST are different from Response Evaluation Criteria in Solid Tumors (RECIST). Purpose of this pictorial essay is to enumerate the characteristic CT features of GIST, and discuss atypical features and response evaluation criteria.

Keywords

GIST - gastrointestinal - tumor - imatinib


Publication History

Article published online:
22 July 2021

© 2019. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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