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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2017; 27(03): 268-273
DOI: 10.4103/ijri.IJRI_454_16
Neuroradiology & Head and Neck Imaging

Role of whole-brain computed tomography perfusion in head injury patients to predict outcome

T S Bindu
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Sameer Vyas
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Niranjan Khandelwal
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Vikas Bhatia
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Sivashanmugam Dhandapani
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Ajay Kumar
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Chirag K Ahuja
Department of Radiodiagnosis and Imaging, Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations Financial support and sponsorship Nil.
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Abstract

Purpose: To evaluate utility, pattern, and extent of perfusion abnormalities in traumatic brain injury by using whole-brain computed tomography perfusion (CTP) and to assess co-relation of CTP data clinically with Glasgow outcome score (GOS). Materials and Methods: Prospective analytic evaluation of the traumatic head injury patients who were immediately taken up for CTP was done. Patient's demographic, clinical, and radiological findings were tabulated and analyzed. GOS was measured by a neurosurgeon after 3 months of trauma who was blinded to CTP results. Results: Of the 78 patients included in this study, 28 patients were found to have GOS 5, 19 of them had GOS 4, 27 of them had GOS 3, and 4 of them had a GOS 2. Higher mean cerebral blood flow (CBF) and cerebral blood volume (CBV) values were observed in those who had a better GOS, i.e., 4 or 5, whereas those in the GOS range ≤3 had lower mean CBF and CBV values. Conclusion: Statistically significant positive correlation was found between cerebral perfusion parameters with that of GOS. CBF of frontal area shows better correlation with GOS. CBF was the most important predictor among all the perfusion parameters.

Keywords

CT - CT perfusion - Glasgow outcome score - head trauma


Publication History

Article published online:
27 July 2021

© 2017. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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