Clopidogrel induced autoimmune hypoglycemia

Abdulla Alnuaimi; Bachar Afandi; Yusra Othman

doi:10.4103/jdep.jdep_8_21

Journal of Diabetes and Endocrine Practice, Table of Contents

CC BY-NC-ND 4.0 · Journal of Diabetes and Endocrine Practice 2021; 04(02): 83-85
DOI: 10.4103/jdep.jdep_8_21

Case Report

Clopidogrel induced autoimmune hypoglycemia

Authors

Abdulla Alnuaimi

¹Division of Endocrinology, Tawam Hospital, Alain
Bachar Afandi

¹Division of Endocrinology, Tawam Hospital, Alain
Yusra Othman

²Department of Laboratory Medicine, Tawam Hospital, Alain

Abstract

We report insulin autoimmune syndrome in a diet-controlled type 2 diabetes mellitus patient. She developed recurrent attacks of severe hypoglycemia 1 week after the initiation of clopidogrel. The evaluation revealed high insulin and C-peptide levels consistent with hyperinsulinemic hypoglycemia. The insulin-to-C-peptide ratio was reversed and >50. Anti-insulin antibody titers were highly positive.

Keywords

Clopidogrel - hyperinsulinemic hypoglycemia - insulin autoimmune syndrome - severe hypoglycemia - type 2 diabetes mellitus

Full Text

References

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