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CC BY-NC-ND 4.0 · Libyan International Medical University Journal 2021; 06(01): 12-18
DOI: 10.4103/liuj.liuj_62_21
Review Article

Diabetic peripheral neuropathy: A systematic review of Nigerian patients

Taoreed Azeez
Department of Medicine, Endocrinology Unit, University College Hospital, Ibadan, Nigeria
,
Emmanuel Eguzozie
Department of Medicine, Endocrinology Unit, University College Hospital, Ibadan, Nigeria
,
Oladotun Olalusi
1   Department of Medicine, Neurology Unit, University College Hospital, Ibadan, Nigeria
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Abstract

Diabetes mellitus is associated with microvascular and macrovascular complications. Diabetic neuropathy is the most common long-term complication of diabetes. The study was aimed at determining the prevalence of diabetic peripheral neuropathy and identifying its associated factors. Medical databases, including PubMed, Google Scholar, African Journal Online, and SCOPUS were searched and eligible studies were selected using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses algorithm. The prevalence of diabetic peripheral neuropathy in Nigeria was dependent on the modality used in diagnosing peripheral neuropathy. The overall prevalence of diabetic peripheral neuropathy in Nigeria was 31.2%–97.5%. The modality-dependent prevalences were 37%–97.5% (by biothesiometry), 41.7%–75% (by Michigan Neuropathy Screening Instrument), 31.2%–43.3% (by United Kingdom screening test), and 43.3%–69.9% (by diabetic neuropathic examination score). The associated factors were duration and control of diabetes, the age of the patient, presence of cardiovascular risk factors such as hypertension and dyslipidemia and other microvascular complications (e.g., diabetic retinopathy and nephropathy). The prevalence of diabetic peripheral neuropathy was found to be high in Nigeria and the associated risk factors were age, glycemic control, and cardiovascular risk factors.

Key-words:

Diabetic neuropathy - diagnosis - Nigeria - prevalence - risk factors

Financial support and sponsorship

Nil.




Publication History

Received: 15 March 2021

Accepted: 23 May 2021

Article published online:
14 June 2022

© 2021. Libyan International Medical University. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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