First-line management of metastatic non-small cell lung cancer: An Indian perspective

Nikhil Suresh Ghadyalpatil; Avinash Pandey; Iyer Krishnamani; Chilukuri Srinivas; Shabnam J. Rafiq; Sachin S. Hingmire; Nagarjuna Maturu; Ragotham Reddy; Kiran K. Kumar; K. Sreekanth; Bharath Chandra Gurram; P. M. Parikh

doi:10.4103/sajc.sajc_294_18

South Asian Journal of Cancer, Table of Contents

CC BY-NC-ND 4.0 · South Asian J Cancer 2019; 08(02): 073-079
DOI: 10.4103/sajc.sajc_294_18

REVIEW ARTICLE

First-line management of metastatic non-small cell lung cancer: An Indian perspective

Nikhil Suresh Ghadyalpatil

Department of Medical Oncology, Yashoda Hospital, Hyderabad, Telangana

,

Avinash Pandey

Department of Medical Oncology, IGIMS, Patna, Bihar

,

Iyer Krishnamani

Department of Medical Oncology, Care Hospital, Hyderabad, Telangana

,

Chilukuri Srinivas

Department of Radiation Oncology, Apollo Proton Cancer Centre, Chennai, Tamil Nadu

,

Shabnam J. Rafiq

Department of Medical Oncology, Yashoda Hospital, Hyderabad, Telangana

,

Sachin S. Hingmire

Department of Medical Oncology, Deenanath Mangeshkar Hospital, Pune, Maharashtra

,

Nagarjuna Maturu

Department of Pulmonology, Yashoda Hospital, Hyderabad, Telangana

,

Ragotham Reddy

Department of Pulmonology, Yashoda Hospital, Hyderabad, Telangana

,

Kiran K. Kumar

Department of Radiation Oncology, Yashoda Hospital, Hyderabad, Telangana

,

K. Sreekanth

Department of Surgical Oncology, Yashoda Hospital, Hyderabad, Telangana

,

Bharath Chandra Gurram

Department of Radiation Oncology, Yashoda Hospital, Hyderabad, Telangana

,

P. M. Parikh

Department of Medical Oncology, Asian Institute of Oncology, Mumbai, Maharashtra

› Author Affiliations

Abstract

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Abstract

Lung cancer has been the most common cancer in the world for several decades. The non-small cell lung cancer (NSCLC) constitutes approximately about 80% of the total cases of lung cancer. Therapeutic interventions in NSCLC have shifted to the target-based approach from histology-based approach, and this has completely changed the face of the management of NSCLC. Developing countries, such as India, have very limited data compiled about the prevalence and treatment practices of lung cancer, despite a large burden of the disease. However, in recent times, there has been a lot of data generated in this regard. This article is an attempt to collate and shine light on the available data for the first-line treatment of NSCLC in India keeping in mind the current standards of care in this area.

Key words

Advanced non-small cell lung cancer - anaplastic lymphoma kinase - chemotherapy - epidermal growth factor receptor - tyrosine kinase inhibitor

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References

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