CC BY-NC-ND 4.0 · South Asian J Cancer 2020; 09(01): 53-55
DOI: 10.4103/sajc.sajc_48_19
ORIGINAL ARTICLE: Pediatric and Adolescent Cancers

Pediatric cancers in Bihar: A retrospective tertiary cancer center study

Avinash Pandey
Department of Medical Oncology, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Anjana Singh
Department of Medical Oncology, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Vijendra Kumar
Department of Paediatric Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Jayant Prakash
Department of Paediatrics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Ritesh Ranu
Department of Orthopaedics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Vinit Thakur
Department of Paediatric Surgery, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Anand Kumar Gupta
Department of Paediatrics, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
,
Shivkant Singh
Department of Medical Oncology, State Cancer Institute, Indira Gandhi Institute of Medical Sciences, Patna, Bihar
› Author Affiliations
Financial support and sponsorship: Nil.

Abstract

Background: There is lack of information regarding pattern of distribution of pediatric cancers in Bihar. Aim: The aim of this study is to identify the pattern of distribution of pediatric cancers. Objectives: To analyze demographic data, type, and pattern of pediatric cancers in Bihar by retrospective clinical audit. Materials and Methods: All individual consecutive patients between ages 0 and 18 years registered in the Department of Medical and Pediatric Oncology from January 1, 2018 till December 31, 2018, were enrolled in this study. Data pertaining to age, sex, and type of cancer were retrieved from clinical database by retrospective audit and stratified into hematolymphoid and solid pediatric cancer cohorts. Frequency distribution and descriptive statistics were used to analyze the data using SPSS version 17.0. Results: A total of 247 pediatric cancers were registered, of which 142/247 (57%) and 15/247 (43%) were pediatric hematolymphoid and solid cancers, respectively. The median age was 9 years, while male-to-female ratio was 2.26. Acute lymphoblastic leukemia (ALL), 76/247 (31%) was the most common pediatric cancer overall. Hodgkin's lymphoma, 27/142 (19%) was the second most common hematolymphoid malignancy, after ALL was 76/142 (54%). Among solid tumors, Wilms' tumor was the most common, 28/105 (27%) followed by Ewing's sarcoma, 16/105 (15%), and germ cell tumor, 15/105 (14%). Central nervous system malignancies were among the least common solid tumor cancers, 3/105 (3%). Conclusion: ALL and Hodgkin's lymphoma are the most common pediatric cancers. Among solid malignancies, Wilms tumor, Ewing's sarcoma, and Germ cell tumor are predominant.



Publication History

Article published online:
14 December 2020

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  • References

  • 1 Arora B, Kanwar V. Childhood cancers in India: Burden, barriers, and breakthroughs. Indian J Cancer 2009;46:257-9.
  • 2 Arora RS, Eden TO, Kapoor G. Epidemiology of childhood cancer in India. Indian J Cancer 2009;46:264-73.
  • 3 Arora B, Kurkure P, Parikh P. Childhood cancers: Perspectives in India. J Indian Med Assoc 2005;103:479-82.
  • 4 Swaminathan R, Rama R, Shanta V. Childhood cancers in Chennai, India, 1990-2001: Incidence and survival. Int J Cancer 2008;122:2607-11.
  • 5 Nandakumar A, Anantha N, Appaji L, Swamy K, Mukherjee G, Venugopal T, et al. Descriptive epidemiology of childhood cancers in Bangalore, India. Cancer Causes Control 1996;7:405-10.
  • 6 Barr R, Riberio R, Agarwal B, Masera G, Hesseling P, Magrath I. Pediatric oncology in countries with limited resources. In: Pizzo PA, Poplack DG, editors. Principles and Practice of Pediatric Oncology. 5th ed. Philadelphia: Lippincott Williams and Wilkins; 2006. p. 1605-17.
  • 7 Miller RW, Young JL Jr., Novakovic B. Childhood cancer. Cancer 1995;75:395-405.
  • 8 Young JL Jr., Ries LG, Silverberg E, Horm JW, Miller RW. Cancer incidence, survival, and mortality for children younger than age 15 years. Cancer 1986;58:598-602.
  • 9 Kaatsch P. Epidemiology of childhood cancer. Cancer Treat Rev 2010;36:277-85.
  • 10 Black WC. Increasing incidence of childhood primary malignant brain tumors – Enigma or no-brainer? J Natl Cancer Inst 1998;90:1249-51.
  • 11 Satyanarayana L, Asthana S, Labani S P. Childhood cancer incidence in India: A review of population-based cancer registries. Indian Pediatr 2014;51:218-20.
  • 12 Parkin DM, Stiller CA, Draper GJ, Bieber CA. The international incidence of childhood cancer. Int J Cancer 1988;42:511-20.
  • 13 Howard SC, Metzger ML, Wilimas JA, Quintana Y, Pui CH, Robison LL, et al. Childhood cancer epidemiology in low-income countries. Cancer 2008;112:461-72.
  • 14 Tyagi BB, Manoharan N, Raina V. Childhood cancer incidence in Delhi, 1996-2000. Indian J Med Paediatr Oncol 2006;27:13-8.
  • 15 Datta K, Choudhuri M, Guha S, Biswas J. Childhood cancer burden in part of eastern India – Population based cancer registry data for Kolkata (1997-2004). Asian Pac J Cancer Prev 2010;11:1283-8.
  • 16 Pearce MS, Parker L. Childhood cancer registrations in the developing world: Still more boys than girls. Int J Cancer 2001;91:402-6.
  • 17 Swaminathan R, Sankaranarayanan R. Under-diagnosis and under-ascertainment of cases may be the reasons for low childhood cancer incidence in rural India. Cancer Epidemiol 2010;34:107-8.
  • 18 Rasul G, Sharma E. Understanding the poor economic performance of Bihar and Uttar Pradesh, India: A macro-perspective. Reg Stud Reg Sci 2014;1:221-39.
  • 19 Nayar KR, Kumar A. Health analysis-Kerala and Bihar: A comparison. YOJANA 2005; vol 49. Available from: https://www.papers.ssrn.com/sol3/papers.cfm?abstract_id=1354541. [Last assessed on 2019 Feb 06].